Trichloroacetic Acid (TCA) Peels

Leonhardt, Janie M.; Rossy, Kathleen M.; Lawrence, Naomi

doi:10.1016/b978-1-4377-1924-6.00007-0

Cited by 3 publications

(7 citation statements)

References 25 publications

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“…It is easy to perform, as the peel depth is assessed with the intensity of skin frosting and there is no need to neutralize a TCA peel. 12 Since there is high risk of post-inflammator y hyperpigmentation with medium and deep-depth TCA peel, we use superficial TCA 20% as there is risk of intense ultra-violet exposure in a tropical place like ours.…”

Section: Discussionmentioning

confidence: 99%

A comparative study between the use of the combination of trichloroacetic acid peeling with hydroquinone and hydroquinone alone in patients with melasma

et al. 2023

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Background: Melasma is a common acquired pigmentary disorder that is aesthetically displeasing. Kligman’s and Modified Kligman’s formula using topical steroids, hydroquinone and retinoids, and various other depigmenting agents is being widely used all over for melasma with varying results. Chemical peeling is newly added to the therapeutic armamentarium and is showing encouraging results worldwide in patients with melasma. However, comparative studies are lacking in abundance in our part of the world. Aims and Objectives: To determine if serial trichloroacetic acid peels provide additional benefits when combined with time-tested topical therapy with hydroquinone 4% in patients with melasma. Materials and Methods: Fifty melasma patients were divided into two groups of 25 each. One group received serial trichloroacetic acid peel combined with topical hydroquinone 4%. The other group only received topical hydroquinone 4% cream. The results were evaluated by a clinical investigator both subjectively and with photographs taken at baseline, 12 weeks, and 21 weeks. For clinical evaluation, the melasma area and severity index (MASI) was used. Results: A significant decrease in MASI score from baseline to 21 weeks was observed in both groups (P<0.001). The group receiving the trichloroacetic acid peel 20% showed a trend toward more rapid and greater improvement, with statistically significant results (P<0.001). Only a few side effects were observed in the peel group. Conclusion: This study demonstrates that serial trichloroacetic acid peels provide an additional effect to a topical regimen of 4% hydroquinone cream for treating melasma in Fitzpatrick skin types III and above if used judiciously and under supervision. It demonstrates that superficial chemical peels can be used as an adjunct with better efficacy to treat patients with melasma.

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Section: Discussionmentioning

confidence: 99%

A comparative study between the use of the combination of trichloroacetic acid peeling with hydroquinone and hydroquinone alone in patients with melasma

et al. 2023

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“…Ważne jest także, z jaką siłą dociska się aplikator do skóry oraz jak wiele potarć wykonuje się w jednym miejscu. Proponowana kolejność aplikacji to dół twarzy od żuchwy do linii ust, następnie środkowa część twarzy, później skóra czoła i na końcu nos [31,32]. Pacjent może odczuwać pieczenie skóry, dlatego warto chłodzić twarz.…”

Section: Kwas Trójchlorooctowyunclassified

“…Zblednięcie skóry na pierwszym poziomie ustępuje po około 5 minutach, a na drugim poziomie po około 10 minutach. Jeżeli zblednięcie na poziomie trzecim trwa dłużej niż 15 minut, należy pacjenta bardzo dokładnie obserwować pod kątem wystąpienia opóźnionego gojenia, tworzenia blizn z hipopigmentacją lub powstawania bliznowców [31,33]. ficial epidermolysis.…”

Section: Kwas Trójchlorooctowyunclassified

“…It is also important with what force the applicator is pressed to the skin and how many rubs in one place are made. The suggested order of application is the lower part of the face from the jawline to the line of the mouth, then the middle part of the face, then the skin of the forehead and finally the nose [31,32]. The patient may experience a burning sensation of the skin, so it is worth cooling the face.…”

Section: Trichloroacetic Acidmentioning

confidence: 99%

“…10 minutes. If a level 3 pallor lasts for more than 15 minutes, the patient should be closely monitored for delayed healing, hypopigmentation scar formation, or keloid formation [31,33]. After whitening occurs, discomfort can be reduced by using cold saline compresses or compresses with chilled gel-filled pouches.…”

Section: Trichloroacetic Acidmentioning

confidence: 99%

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Principles of applying chemoexfoliation (chemical peelings)

Chlebuś¹,

Serafin²

2023

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Chemoexfoliation (chemical peelings) is a costeffective and high safety profile method of affecting the skin to improve its appearance both for cosmetic conditions and to support the treatment of diseases associated with abnormal activity of sebaceous glands and hyperkeratosis. In this article, the authors provide a historical outline of the development of exfoliation techniques, the classification of peels on the basis of the depth of penetration, chemical functions of compounds, as well as practical tips on how to properly select the type of exfoliating substance depending on the disease or aesthetic problem of the skin. Also, possible complications, tips for their prevention and treatment are discussed.

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Eficacy of trichloroacetic acid peel versus 15% topical azelaic acid gel in the treatment of acne vulgaris – a comparative study

Hussein

Buicu

Maier

et al. 2015

Acta Medica Marisiensis

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Objectives: The aim of this study was to compare the efficacy and tolerability of 20% trichloroacetic acid (TCA) peel with 15% azelaic acid gel, a standard antiacne topical treatment. Materials and methods: 51 patients aged between 16-40 years, with mild and moderate acne, were randomized into two groups. Before the treatment were investigated the patients clinical features and hygienic habits, the previous antiacne treatments and feed-back to them. No cases under treatment with contraceptive pills or antiacne medication that could interfere with the results, were included. For a period of eight weeks, 27 patients (group A) were treated with 15% azelaic acid gel, twice daily, and 24 patients (group B) underwent four sessions of 20% TCA peels, at 14 days interval. The efficacy was evaluated by acne lesions counting, at baseline and at 8 weeks. Adverse effects incidence (erythema, local skin irritation), as well as the satisfaction degree of patients, were investigated. Results: Was observed a mean reduction in the number of acne lesions of 32,36% for the group A and 69,36% for the group B. There was no statistically significant difference between the average number of acne lesions before treatment between the two groups. The mean number of acne lesions after the treatment was significantly different (p<0,0001), 20% TCA peels showed superior results than 15% azelaic acid gel. Additionally, 96% of patients who underwent TCA peels were very satisfied with the results obtained. Conclusions: TCA peel is an efficient and well tolerated method for the treatment of acne vulgaris.

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Trichloroacetic Acid (TCA) Peels

Cited by 3 publications

References 25 publications

A comparative study between the use of the combination of trichloroacetic acid peeling with hydroquinone and hydroquinone alone in patients with melasma

A comparative study between the use of the combination of trichloroacetic acid peeling with hydroquinone and hydroquinone alone in patients with melasma

Principles of applying chemoexfoliation (chemical peelings)

Eficacy of trichloroacetic acid peel versus 15% topical azelaic acid gel in the treatment of acne vulgaris – a comparative study

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