Trichomonas vaginalis Infections are Rare Among Young Patients Attending an STI Clinic in Sweden

Pellrud, Helena; Golparian, Daniel; Nilsson, Christian; Falk, My; Fredlund, Hans; Unemo, Magnus

doi:10.2340/00015555-1946

Cited by 11 publications

(13 citation statements)

References 11 publications

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“…Despite the use of wet mount microscopy, culture and the most sensitive NAAT, not a single case of trichomoniasis was detected. This is in concordance with recent results from other EU settings, also with the use of NAATs, which have shown exceedingly low prevalence of T. vaginalis infections in women, ranging from 0% (community clinic attendees in England), through 0.16% (STI clinic in Sweden) up to 0.8% and 1.3% (genitourinary clinic in England and lowrisk childbearing women in Italy, respectively) (8,12,13). Even among female sex workers in Germany, the prevalence has been shown to be as low as 3% (10).…”

Section: Discussionsupporting

confidence: 92%

Trichomonas vaginalis is very rare among women with vaginal discharge in Podlaskie province, Poland

Serwin

Bulhak-Koziol

Sokolowska

et al. 2017

APMIS

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Trichomonas vaginalis is the most common curable sexually transmitted pathogen globally. However, in the European Union (EU), trichomoniasis appears to be a rare condition. The aim of this study was to examine the prevalence of T. vaginalis among females attending an STI centre in Bialystok, Poland, using the highly sensitive and specific APTIMA T. vaginalis assay. Consecutive females, referred by gynaecologists mainly because of abnormal vaginal discharge, were diagnosed using wet mount microscopy, culture and APTIMA T. vaginalis assay. Among 272 women studied, 82% were pre- and 18% postmenopausal. The average age was 36.0 ± 13.9 (range: 18-86) years. Abnormal discharge (alone or accompanied by itch or vulvovaginal burning) was the most frequent complain in both groups (66.2% and 48.0%). Erythema and discharge were the most frequent abnormal signs (58.6% and 56.0%). Not a single T. vaginalis-positive sample was detected using wet mount microscopy, culture or APTIMA T. vaginalis assay. Despite using the highly sensitive APTIMA T. vaginalis assay for detection, the pathogen could not be identified in females in the studied setting, similar to results from other EU settings. The need for general screening using NAAT for this pathogen while diagnosing vulvovaginal symptoms in females in Poland appears to be low.

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Section: Discussionsupporting

confidence: 92%

Trichomonas vaginalis is very rare among women with vaginal discharge in Podlaskie province, Poland

Serwin

Bulhak-Koziol

Sokolowska

et al. 2017

APMIS

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“…0.6-3.6% (4,5). The prevalence of T. vaginalis infection in the Nordic countries in Northern Europe is largely unknown, with the exception of a single NAAT-based study in Sweden, where 1,121 consecutive STD clinic attendees in Örebro demonstrated prevalence rates of 0.16% in women and 0% in men, using the APTIMA TV Assay (6). The aim of the present study was to examine the prevalence of T. vaginalis infection and selected STDs among consecutive Icelandic women attending an STD clinic and a cervical cancer screening programme.…”

mentioning

confidence: 99%

Trichomonas vaginalis is Rare Among Women in Iceland

Hilmarsdóttir¹,

Sigmundsdottir²,

Eiriksdottir³

et al. 2017

Acta Derm Venerol

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“…This is mainly in agreement with the high CT prevalences and relatively high NG prevalences in many European countries (2,3). However, the prevalence of TV was surprisingly high compared to neighbouring Poland (31), and Sweden (32) and Iceland (33) where TV has been extremely rare using the same Aptima TV assay. Instead, the high TV prevalence in Ukraine correlated more with TV prevalences described in Spain, the United States and other countries outside Europe (34)(35)(36).…”

Section: Discussionmentioning

confidence: 85%

“…Instead, the high TV prevalence in Ukraine correlated more with TV prevalences described in Spain, the United States and other countries outside Europe (34)(35)(36). The reasons for this are likely multifaceted but include less frequent use of metronidazole in Ukraine (for suspected or confirmed bacterial vaginosis and/or trichomoniasis) compared to in Sweden (32) and Iceland (33), less universal access to high-quality health care, and other socioeconomic factors.…”

Section: Discussionmentioning

confidence: 99%

High prevalence of Chlamydia trachomatis, Neisseria gonorrhoeae and particularly Trichomonas vaginalis diagnosed using US FDA‐approved Aptima molecular tests and evaluation of conventional routine diagnostic tests in Ternopil, Ukraine

Boiko

Golparian

Krynytska

et al. 2019

APMIS

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M. High prevalence of Chlamydia trachomatis, Neisseria gonorrhoeae and particularly Trichomonas vaginalis diagnosed using US FDA-approved Aptima molecular tests and evaluation of conventional routine diagnostic tests in Ternopil, Ukraine. APMIS 2019; 127: 627-634.Sexually transmitted infections (STIs) remain major public health problems globally. Appropriate laboratory diagnosis of STIs is rare in Ukraine. We investigated the prevalence of Chlamydia trachomatis (CT), Neisseria gonorrhoeae (NG) and Trichomonas vaginalis (TV) using the US FDA-approved Aptima Combo 2 and Aptima TV assays and compared the results with the conventional routine diagnostic tests (CDTs) in Ukraine. Urogenital swabs from consecutive mostly symptomatic females (n = 296) and males (n = 159) were examined. The prevalences were as follows: 10% (n = 47) of TV, 5.3% (n = 24) of CT and 1.5% (n = 7) of NG. The specificity of some CDTs was high, for example, 100% for NG culture, TV IgG ELISA, CT IgM ELISA and CT microscopy, but lower for other CDTs, that is, from 44% to 99.8%. The sensitivity of all CDTs was suboptimal, that is, 71% (n = 5) for NG microscopy, 57% (n = 4) for NG culture, 53% (n = 8) for CT IgG ELISA, 33% (n = 1) for TV IgG ELISA, 28% (n = 13) for TV microscopy, 25% (n = 1) for CT IgA ELISA, 20% (n = 3) for CT IgM ELISA and 0% (n = 0) for CT microscopy. The prevalences of particularly TV and CT were high, but substantial also for NG, in Ternopil, Ukraine. The sensitivities of all CDTs were low, and widespread implementation of validated, quality-assured and cost-effective molecular diagnostic STI tests in Ukraine is imperative.

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Trichomonas vaginalis Infections are Rare Among Young Patients Attending an STI Clinic in Sweden

Cited by 11 publications

References 11 publications

Trichomonas vaginalis is very rare among women with vaginal discharge in Podlaskie province, Poland

Trichomonas vaginalis is very rare among women with vaginal discharge in Podlaskie province, Poland

Trichomonas vaginalis is Rare Among Women in Iceland

High prevalence of Chlamydia trachomatis, Neisseria gonorrhoeae and particularly Trichomonas vaginalis diagnosed using US FDA‐approved Aptima molecular tests and evaluation of conventional routine diagnostic tests in Ternopil, Ukraine

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