Trichoscopic Hair Evaluation in Patients with Ectodermal Dysplasia

Rakowska, Adriana; Górska, Renata; Rudnicka, Lidia; Zadurska, Małgorzata

doi:10.1016/j.jpeds.2015.04.002

Cited by 11 publications

(11 citation statements)

References 21 publications

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“…Clinically, hair may be sparse, light‐pigmented, thin, dry and brittle. Common hair abnormality observed by trichoscopy are hypotrichosis resulting from prevalence of follicular units with single hair and abnormalities of hair shaft pigmentation (grey hair in percentage higher than 10% and heterogeneity of hair shaft pigmentation due to the coexistence of pigmented and non‐pigmented hairs) . Using light microscopy and scanning electron microscopy, a wide range of morphologic hair abnormalities can be identified: pili torti or other twists of the hair shaft, pili trianguli et canaliculi, grooves of the hair shaft, cuticle damage, small shaft diameter and the shape of the hair on cross section …”

Section: Discussionmentioning

confidence: 99%

Topical cetirizine and oral vitamin D: a valid treatment for hypotrichosis caused by ectodermal dysplasia

Rossi

Miraglia

Fortuna

et al. 2016

Acad Dermatol Venereol

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Section: Discussionmentioning

confidence: 99%

Topical cetirizine and oral vitamin D: a valid treatment for hypotrichosis caused by ectodermal dysplasia

Rossi

Miraglia

Fortuna

et al. 2016

Acad Dermatol Venereol

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“…The diagnosis of pili torti is based on trichoscopic and microscopic examination. Trichoscopy, hair and scalp dermoscopy, is a rapid technique that is useful in the diagnosis of scalp and hair diseases as well as genetic disorders, including ectodermal dysplasias [10,131]. It can be performed with a manual dermoscope (10 magnification) or a videodermoscope (20-1000 magnification) [132].…”

Section: Diagnosismentioning

confidence: 99%

Pili Torti: A Feature of Numerous Congenital and Acquired Conditions

Hoffmann

Waśkiel‐Burnat

Żółkiewicz

et al. 2021

JCM

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Pili torti is a rare condition characterized by the presence of the hair shaft, which is flattened at irregular intervals and twisted 180° along its long axis. It is a form of hair shaft disorder with increased fragility. The condition is classified into inherited and acquired. Inherited forms may be either isolated or associated with numerous genetic diseases or syndromes (e.g., Menkes disease, Björnstad syndrome, Netherton syndrome, and Bazex–Dupré–Christol syndrome). Moreover, pili torti may be a feature of various ectodermal dysplasias (such as Rapp–Hodgkin syndrome and Ankyloblepharon-ectodermal defects-cleft lip/palate syndrome). Acquired pili torti was described in numerous forms of alopecia (e.g., lichen planopilaris, discoid lupus erythematosus, dissecting cellulitis, folliculitis decalvans, alopecia areata) as well as neoplastic and systemic diseases (such as cutaneous T-cell lymphoma, scalp metastasis of breast cancer, anorexia nervosa, malnutrition, cataracts, and chronic graft-vs-host disease). The condition may also be induced by several drugs (epidermal growth factor receptor inhibitors, oral retinoids, sodium valproate, and carbamide perhydrate). The diagnosis of pili torti is based on trichoscopic or microscopic examination. As pili torti is a marker of numerous congenital and acquired disorders, in every case, the search for the signs of underlying conditions is recommended.

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“…Hair is the most frequent appendage affected by ectodermal dysplasias [115], with manifestations of alopecia and hypotrichosis. Common trichoscopic findings in ectodermal dysplasia include follicular units with a single hair, abnormalities in hair shaft pigmentation, pili torti, trichoschisis, pili canaliculi, trichorrhexis nodosa, and pseudomonilethrix [116].…”

Section: Ectodermal Dysplasiasmentioning

confidence: 99%

Genetic Hair Disorders: A Review

Ahmed

Almohanna

Griggs

et al. 2019

Dermatol Ther (Heidelb)

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Hair loss in early childhood represents a broad differential diagnosis which can be a diagnostic and therapeutic challenge for a physician. It is important to consider the diagnosis of a genetic hair disorder. Genetic hair disorders are a large group of inherited disorders, many of which are rare. Genetic hair abnormalities in children can be an isolated phenomenon or part of genetic syndromes. Hair changes may be a significant finding or even the initial presentation of a syndrome giving a clue to the diagnosis, such as Netherton syndrome and trichothiodystrophy. Detailed history including family history and physical examination of hair and other ectodermal structures such as nails, sweat glands, and sebaceous glands with the use of dermoscopic devices and biopsy all provide important clues to establish the correct diagnosis. Understanding the pathophysiology of genetic hair defects will allow for better comprehension of their treatment and prognosis. For example, in patients with an isolated hair defect, the main problem is aesthetic. In contrast, when the hair defect is associated with a syndrome, the prognosis will depend mainly on the associated condition. Treatment of many genetic hair disorders is focused on treating the primary cause and minimizing trauma to the hair.

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Trichoscopic Hair Evaluation in Patients with Ectodermal Dysplasia

Cited by 11 publications

References 21 publications

Topical cetirizine and oral vitamin D: a valid treatment for hypotrichosis caused by ectodermal dysplasia

Topical cetirizine and oral vitamin D: a valid treatment for hypotrichosis caused by ectodermal dysplasia

Pili Torti: A Feature of Numerous Congenital and Acquired Conditions

Genetic Hair Disorders: A Review

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