Triggering risk factors for ischemic stroke

Koton, Silvia; Tanné, David; Bornstein, Natan M.; Green, Manfred S.

doi:10.1212/01.wnl.0000145842.25520.a2

Cited by 86 publications

(86 citation statements)

References 21 publications

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“…An analysis of population attributable risk estimated that emotional stress had a role in 3.9% of acute cardiac events (79). The use of case-crossover methods for stroke has been limited, but one study reported an odds ratio as high as 14.0 (95% CI 4.4-89.7) for negative emotion in the two hours before stroke onset (58).…”

Section: Acute Cardiac Eventsmentioning

confidence: 99%

Stress and Cardiovascular Disease: An Update on Current Knowledge

Steptoe

Kivimäki

2013

Annu. Rev. Public Health

649

443

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Considerable progress has been made during the past decade in research on cardiovascular effects of stress. Early-life stressors, such as childhood abuse and early socioeconomic adversity, are linked to increased cardiovascular morbidity in adulthood. Our updated meta-analyses of prospective studies published until 2011 show a 1.5-fold (95% confidence interval 1.2-1.9) increased risk of coronary heart disease among adults experiencing social isolation and a 1.3-fold (1.2-1.5) excess risk for workplace stress; adverse metabolic changes are one of the underlying plausible mechanisms. Stress, anger, and depressed mood can act as acute triggers of major cardiac events; the pooled relative risk of acute coronary syndrome onset being preceded by stress is 2.5 (1.8-3.5) in case-crossover studies. Stress is also implicated in the prognosis of cardiovascular disease and in the development of stress (takotsubo) cardiomyopathy. A major challenge over the next decade is to incorporate stress processes into the mainstream of cardiovascular pathophysiological research and understanding.

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Section: Acute Cardiac Eventsmentioning

confidence: 99%

Stress and Cardiovascular Disease: An Update on Current Knowledge

Steptoe

Kivimäki

2013

Annu. Rev. Public Health

649

443

View full text Add to dashboard Cite

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“…In a study of 200 individuals hospitalized for stroke or transient ischemic attack, approximately 30 reported having extreme episodes of anger, fear, irritability, or nervousness as a result of a startling event within 2 hours before experiencing their stroke. 523 In addition, exposure to a potential trigger may increase stroke risk by as much as 14 times during the 2-hour period immediately after the exposure. Kuroda et al 524 found that women had a higher proportion of poststroke anxiety and depression than men, and although additional findings suggest that women have different coping styles than men after stroke, there remains a paucity of research to clarify sex differences and thus guide appropriate interventions.…”

Section: Inpatient Outpatient and Chronic Care Settingsmentioning

confidence: 99%

Comprehensive Overview of Nursing and Interdisciplinary Rehabilitation Care of the Stroke Patient

Miller¹,

Murray²,

Richards³

et al. 2010

Stroke

685

412

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“…The literature search finally resulted in 26 studies that met inclusion criteria (Supplemental Figure, available at http://stroke.ahajournals.org), corresponding to 12 potential triggers: alcohol abuse (nϭ10 studies), [21][22][23][24][25][26][27][28][29][30] clinical infection/inflammation (nϭ12), 10,11,29,[31][32][33][34][35][36][37][38][39] stressful life events (nϭ1), 34 psychological distress (nϭ1), 40 birthday (nϭ1), 41 positive or negative emotions (nϭ1), 42 anger (nϭ1), 42 sudden posture change in response to a startling event (nϭ1), 42 heavy physical exertion (nϭ1), 42 heavy eating (nϭ1), 42 and recreational drug abuse (nϭ2). 43,44 Interrater reliability for selection process was perfect (ϭ1.00).…”

Section: Resultsmentioning

confidence: 99%

Triggers of Ischemic Stroke

Guiraud

Amor

Mas

et al. 2010

Stroke

111

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Background and Purpose-Several studies have suggested that exposure to "triggers," could precipitate the onset of ischemic stroke (IS). We performed a systematic review of the potential triggers of IS. Methods-Two independent reviewers identified studies published between January 1980 and June 2010 from MEDLINE and Embase. Where appropriate, odds ratios (ORs) were combined. Results-A total of 26 studies identified 12 potential triggers. Twenty-two studies used a case-control design, and hazard period durations ranged from 2 hours to 3 months. The majority of studies were dedicated to alcohol abuse (nϭ10) and clinical infection (nϭ12). There was a significant association between IS and alcohol abuse of Ͼ40 to 60 g within the preceding 24 hours (ORϭ2.66; 95% CI, 1.54 to 4.61) or Ͼ150 g within the previous week (ORϭ2.47; 95% CI, 1.52 to 4.02) and infection within the previous week (ORϭ2.91; 95% CI, 1.41 to 6.00) or within the previous month (ORϭ2.41; 95% CI, 1.78 to 3.27). Other triggers have been far less investigated. There was a significant association between IS and anger, heavy eating, negative or positive emotions, sudden posture change in response to a startling event, birthday, and psychological distress and no significant association with drug abuse or heavy physical exertion. Regarding methodological issues, patients were rarely blinded to study objectives, and interviewers were rarely blinded to patient status. Conclusions-Research

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Triggering risk factors for ischemic stroke

Abstract: Negative emotions, anger, and sudden changes in body posture in response to a startling event appear to be independent triggers for ischemic stroke.

Cited by 86 publications

References 21 publications

Stress and Cardiovascular Disease: An Update on Current Knowledge

Stress and Cardiovascular Disease: An Update on Current Knowledge

Comprehensive Overview of Nursing and Interdisciplinary Rehabilitation Care of the Stroke Patient

Triggers of Ischemic Stroke

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