Trilene as an Analgesic in Labour

Abstract

CORRESPONDENCE MEDICAL JOURNALOwing to the fact that w-e were dealing with African natives we had to rely upon examination of the conjunctivae for the presence of petechiae. Of the whole series, 78 (45%) presented this sign, many of them before meningism supervened. These latter suffered, as Drs. Turner and Dent describe, from collapse associated with rise of temperature and rapid feeble pulse ; a number of them also had loose incontinent stools, which was a bad prognostic sign. Penicillin was not yet available, and I was unaware of the value of adrenal cortical extract, but all cases were immediately put on sulphonamide as a routine. There were 25 deaths (14.5%O) in all-21 of the patients dying on the day of admission.The mortality rate threw some light on the value of petechiae as a prognostic sign. The figures for this series were total number of cases with petechiae 78, deaths 25 (320%); total number where no petechiae were observed (all verified cases by lumbar puncture) 95, deaths ni/.It may be of interest to mention that two cases in the series had persistent meningism with turbid C.S.F. for several weeks. Both cases made uneventful recoveries soon after the intravenous injection of T.A.B. (100 million), followed by a 200-million dose two days later.-I am, etc., Kirkby-in-Ashfield, Notts.

Pharmacology and toxicology of trichloroethylene: A critical review of the world literature

“…Some reports implicate anoxia.s" hypovolemic shocks'" overdosage,'>' aspiration of vomitus,"'" and overdosage of local anesthetics.i'" Several articles suggest primary arrest with light anesthesia in well-ventilated patients. ": 106,124,130,195,300,312,396 Respiration. Although tachypnea with trichloroethylene has been observed for a long time, its signiflcance is still undetermined.…”

“…Many procedures have been performed in dentistry, either by inhalation,245,334 with self-inhalers.t-" 127,218,233,359,363,364,436 or under complete anesthesia in which trichloroethylene is generally added to nitrous oxide.P: 41,42,43,49,65,80,84,161,232,244,294,365 Obstetrics. Since 1943, trichloroethylene has been widely used in obstetrics either as an anestheticv 64,123,216,289,293,334,376 or more generally as an analgesie administered through a self-inhaler-v 34,48,64,13,74,99,102,106,129,147,154,177,182,191,198,283,299,320,373,381 or through special obstetric inhalers (the Tecota 213 Emotril.>'? Minnit 210<...>…”