Trimethylaluminum

Bracher, Franz

doi:10.1002/(sici)1521-3897(199901)341:1<88::aid-prac88>3.0.co;2-8

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“…Since Weinreb and co-workers reported AlMe 3 promoted amide synthesis from esters and amines in 1977, the AlMe 3 -mediated amide and lactam formation from esters has found many applications in organic synthesis. , Using aluminum amides, carbamates can be directly converted to ureas . To the best of our knowledge, the direct synthesis of amides from acids and amines using AlMe 3 as a coupling reagent has not been reported .…”

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confidence: 99%