Triorganotin and triorganolead derivatives of glutamic and aspartic acid. Crystal structure of trimethyltin glutamate

Huber, F.; Mundus-Glowacki, B.; Preut, H.

doi:10.1016/0022-328x(89)87172-4

Cited by 20 publications

(6 citation statements)

References 29 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…1). In comparable triorganotin derivatives of amino acids and dipeptides the presence of an essentially uniden- tate carboxylate group was proposed on the basis of vibrational and Mossbauer data;' for trimethyltin glycinate this structure was established by X-ray diffra~tion.~ The coordination number five is attained by means of the coordination of the 1 t ' Figure 1 The configuration of the tin environment assumed for the rationalization of the Il9Sn Mossbauer nuclear quadrupole splitting parameters, AE, and isomer shift, 6. The direction of the principal components of the electric field gradient tensor" (x. y, z ) from point-charge model calculationsi0 are indicated.…”

Section: Resultsmentioning

confidence: 99%

“…An opposite behavior is observed upon coordination by oxygen . 6 Owing to poor resolution in the region 1600-1700 cm-', absorptions due to carbonyl groups overlap and it is not then a simple matter to observe the shift of the amide I band. Sn-C frequencies in trimethyltin derivatives give information on the symmetry of the SnC3 group.…”

Section: Ch3--(co)-nh-ch2-(co)-nh-ch-coosnrmentioning

confidence: 99%

See 1 more Smart Citation

Synthesis and spectroscopic characterization of R₃Sn^IV derivatives of N‐acetyldipeptides

Huber

Vornefeld

Ruisi

et al. 1993

Applied Organom Chemis

View full text Add to dashboard Cite

Triorganotin(IV) derivatives of N‐acetyldipeptides R3SnAcDip; RMe, Et, n‐Bu, n‐Oct, Cy or Ph (HAcDipN‐acetylglycylglycine and N‐acetylglycylvaline; RMe, n‐Bu, Cy, HAcDipN‐acetylglycylalanine) were obtained by neutralization of R3SnOH and HAcDip. The complexes were studied by means of 119Sn Mössbauer, IR and 1H, 13C and 119Sn NMR spectroscopy. The CSnC bond angles have been inferred by rationalization of Mössbauer nuclear quadrupole splittings as well as from NMR coupling constants. Correlations of Mössbauer isomer shifts with partial atomic charges on tin atoms have been determined: Polymeric trigonal bipyramidal structures, with near‐planar R3Sn units and axial carboxylate (unidentate) and CO amide donor groups are inferred for all the compounds in the solid state, except for Cy3SnAcGlyVal for which a tetrahedral structure is proposed. In solution the complexes are monomeric; in methanol a solvent molecule is coordinated to tin which then is still in a trigonal bipyramidal environment.

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Ch3--(co)-nh-ch2-(co)-nh-ch-coosnrmentioning

confidence: 99%

Synthesis and spectroscopic characterization of R₃Sn^IV derivatives of N‐acetyldipeptides

Huber

Vornefeld

Ruisi

et al. 1993

Applied Organom Chemis

View full text Add to dashboard Cite

show abstract

“…The absorptions v s a s (SnC) of Me 3 Sn-and Et 3 Sn-derivatives are found between 600 and 450 cm. *v (Sn-C) provide no information concerning the C 3 Sn fragment and are not taken into account ** the determination of v s (Sn-C) is impossible due to the strong absorbtion of R' at 520 cm 1 The parameter Av(COO) = v as (COO)-v s (COO) allowing to estimate [11] mono-or bidentate behaviour of carboxylate groups and, subsequently, the coordination number of tin, also appears in Table 4. The magnitudes of Av(COO) for solid carboxylates XV-XIX (195-212 cm 1 ) indicate the bidentate character of COO-group.…”

Section: The Structures Of Triorganotin Derivatives Of α-Methoxy-and mentioning

confidence: 99%

The Comparative Studies of Organotin and Organogermanium Carboxylates

Petrosyan¹,

Yashina²,

Ponomarev³

et al. 1996

Main Group Metal Chemistry

View full text Add to dashboard Cite

Within the frame of a project on biologically active organometallic compounds twenty five triorganotin and organogermanium carboxylates of the type R 3 M0C(0)CH(0X)Ph (M = Sn, Ge; R = Me, Et, n-Bu; X = H, Me, C(0)Me, C(0)CF 3 , R 3 Ge), several diorganotin carboxylates R 2 Sn[0C(0)CH(0X)Ph] 2 (R = Et, n-Bu; X = Me, C(0)Me and {[R 2 Sn0C(0)CH(0X)Ph] 2 0} 2 (R = Et, n-Bu; X = Me, C(O)Me) and a new type of triorganogermanium carboxylates R 3 GeC^CCH 2 0C(0)CH(0X)R' (R = Me, Et, R' = Ph, Me, X = COCH 3 , COCF 3 ) have been synthesized and characterized by elemental analysis and structural methods (NMR, X-Ray, IR and Mössbauer). Introduction.Organotin and organogermanium compounds are the subject of special interest as potential antitumor agents. The literature analysis shows that antitumor activity is mostly characteristic of the covalent compounds of germanium and tin, in which the fragments forming the intra-and intermolecular coordination bonds with germanium and tin atoms do exist.The organotin and organogermanium carboxylates are of this type. The new organogermanium and organotin derivatives of α-substituted phenylacetic acids are described in this paper. Because of the specific properties of organotin and organogermanium carboxylates we will first describe the germanium compounds, and, afterwards, the derivatives of tin.

show abstract

“…76 " 82 Both Cp*PbCl and Cp* 2 Pb can be obtained fro m the reaction o f PbCl 2 with LiCp* depending on the ratio of the reactants. Treatment of the bis (cyclopentadienyl) compounds with strong acids such as HBF 4 , HO 2 CCF 3 or HO 3 SCF 3 leads to the formation of the monocyclopentadienyllead derivatives (31), (32) and dimeric (33). Highly ring-substituted compounds are air stable.…”

Section: Bivalent Compoundsmentioning

confidence: 99%

Lead

Harrison¹

1995

Comprehensive Organometallic Chemistry II

View full text Add to dashboard Cite

Triorganotin and triorganolead derivatives of glutamic and aspartic acid. Crystal structure of trimethyltin glutamate

Cited by 20 publications

References 29 publications

Synthesis and spectroscopic characterization of R₃Sn^IV derivatives of N‐acetyldipeptides

Synthesis and spectroscopic characterization of R₃Sn^IV derivatives of N‐acetyldipeptides

The Comparative Studies of Organotin and Organogermanium Carboxylates

Lead

Contact Info

Product

Resources

About

Triorganotin and triorganolead derivatives of glutamic and aspartic acid. Crystal structure of trimethyltin glutamate

Cited by 20 publications

References 29 publications

Synthesis and spectroscopic characterization of R3SnIV derivatives of N‐acetyldipeptides

Synthesis and spectroscopic characterization of R3SnIV derivatives of N‐acetyldipeptides

The Comparative Studies of Organotin and Organogermanium Carboxylates

Lead

Contact Info

Product

Resources

About

Synthesis and spectroscopic characterization of R₃Sn^IV derivatives of N‐acetyldipeptides

Synthesis and spectroscopic characterization of R₃Sn^IV derivatives of N‐acetyldipeptides