2022
DOI: 10.21203/rs.3.rs-1156586/v1
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TRIP13 Activates the PI3K/AKT Signal Pathway to Promote Melanoma Progression by Interacting With FLNA

Abstract: Background: Skin melanoma is a malignant tumor originated from skin melanocytes. It is highly malignant and easy to relapse and metastasis. Finding new diagnostic and therapeutic targets has become a hot issue. Accumulating evidence now indicates that thyroid hormone receptor interactor 13 (TRIP13) plays important roles in tumor development. However, its role in melanoma remains unclear.Methods: Bioinformatic analyses were employed to excavate crucial genes in melanoma using several public databases. The expre… Show more

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