2024
DOI: 10.3390/pharmaceutics16020284
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Triphenylphosphonium-Functionalized Gold Nanorod/Zinc Oxide Core–Shell Nanocomposites for Mitochondrial-Targeted Phototherapy

Ara Joe,
Hyo-Won Han,
Yu-Ra Lim
et al.

Abstract: Phototherapies, such as photothermal therapy (PTT) and photodynamic therapy (PDT), combined with novel all-in-one light-responsive nanocomposites have recently emerged as new therapeutic modalities for the treatment of cancer. Herein, we developed novel all-in-one triphenylphosphonium-functionalized gold nanorod/zinc oxide core–shell nanocomposites (CTPP-GNR@ZnO) for mitochondrial-targeted PTT/PDT owing to their good biocompatibility, tunable and high optical absorption, photothermal conversion efficiency, hig… Show more

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Cited by 3 publications
(1 citation statement)
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“…On the other hand, gold nanorods (AuNRs) can provide an even more pronounced photothermal conversion efficiency [ 21 , 22 , 23 , 24 ]. When irradiated by a particular frequency of light equal to the inherent frequency of the conductive electrons of AuNRs, these start to collectively oscillate at the nanorods surface, reaching their maximal amplitude of oscillation.…”
Section: Introductionmentioning
confidence: 99%
“…On the other hand, gold nanorods (AuNRs) can provide an even more pronounced photothermal conversion efficiency [ 21 , 22 , 23 , 24 ]. When irradiated by a particular frequency of light equal to the inherent frequency of the conductive electrons of AuNRs, these start to collectively oscillate at the nanorods surface, reaching their maximal amplitude of oscillation.…”
Section: Introductionmentioning
confidence: 99%