Triple intrathecal chemotherapy for leptomeningeal carcinomatosis in solid tumors: Treatment outcomes, response and their determinants

Srinivasalu, Vijay Kumar; Subramaniam, Narayana; Philip, Arun; Jose, Wesley; Pavithran, Keechilat

doi:10.4103/ijc.ijc_730_18

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2024

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Cited by 9 publications

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“…The utility of triple IT was seen in a study reported from Kochi. 21 Symptomatic improvement was noted in 70% of patients and the 6 month-OS was 38%. However the median PFS was a dismal of 2.0 months only.…”

Section: Discussionmentioning

confidence: 92%

“…In a LMC experience reported from Kochi (State of Kerala), the commonest site leading to LMC was breast (45%) followed by lung cancer (35%). 21 Other large experiences from India (>1100 patients) by Patil and colleagues 22 and Abraham and colleagues, 23 were in lung cancer and breast cancer respectively.…”

Section: Discussionmentioning

confidence: 98%

“… 22 Similar experience was published from Kochi, where the commonest presenting features were headache, vomiting, loss of consciousness, cranial nerve palsies and seizures. 21 …”

Section: Discussionmentioning

confidence: 99%

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