Triple Synchronous Primary Neoplasms of the Cervix, Endometrium, and Ovary: A Rare Case Report and Summary of All the English PubMed-Indexed Literature

Abu‐Zaid, Ahmed; Alsabban, Mohannad; Abuzaid, Mohammed; Alomar, Osama; Salem, Hany; Al‐Badawi, Ismail A.

doi:10.1155/2017/9705078

Cited by 6 publications

(13 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This is especially true when malignancies of uterus or uterine cervix are involved because their symptoms occur earlier as compared to those of ovarian neoplasms. The prognosis of synchronous primary malignancies depends on the histological grade and prognosis of the poorest primary 1,5 .…”

Section: Resultsmentioning

confidence: 99%

“…The rest are of triple synchronous malignancies involving uterus, cervix and ovaries in varying combinations. 1,[6][7][8] . A comparative list of the reported cases has been listed in Table 1.…”

Section: Discussionmentioning

confidence: 99%

“…To designate tumors as synchronous primaries, each tumor should have distinct histological features and the possibility of metastasis must be ruled out after a thorough objective gross and microscopic evaluation. Warrens and Gates established the following criteria for the diagnosis of multiple primary tumors: (1) each of the tumors must present a definite picture of malignancy; (2) each must be clinicopathologically distinct; (3) the probability of one being a metastasis or recurrence must be excluded 9 .…”

Section: Discussionmentioning

confidence: 99%

“…The most important and major criterion to designate them as synchronous primary malignancies is the presence of distinct histomorphology. The four minor criteria include (a) neoplasms which are limited to primary locations, (b) absence of direct extension between neoplasms, (c) absence of lymphovascular neoplastic invasion, and (d) absence metastasis 1,12,13 . Our case meets all the above criteria.…”

Section: E F G Hmentioning

confidence: 99%

“…Triple synchronous primary malignancies involving the uterus, ovary and cervix have rarely been documented. Till date, only 14 cases of three or more synchronous primary malignancies have been reported in PubMed indexed journals 1 .…”

Section: Introductionmentioning

confidence: 99%

See 4 more Smart Citations

Triple Synchronous Primary Malignancies of Ovary, Endometrium and Cervix – A Rare Case Report

Shah¹

2018

jmscr

View full text Add to dashboard Cite

Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: E F G Hmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Triple Synchronous Primary Malignancies of Ovary, Endometrium and Cervix – A Rare Case Report

Shah¹

2018

jmscr

View full text Add to dashboard Cite

Triple synchronous tumour of female genital tract: cervical squamous cell carcinoma, right ovarian dermoid cyst and left ovarian benign Brenner tumour

Adhya¹,

Mohanty²

2019

BMJ Case Rep

View full text Add to dashboard Cite

Synchronous tumours of two different histological type are not uncommon in the female genital tract. But triple synchronous tumours of three or more different histological types is extremely rare. We describe a case of a 48-year-old female patient who presented with cervical growth and bilateral ovarian masses. Pathological evaluation of the surgical specimen revealed synchronous cervical squamous cell carcinoma, right ovarian dermoid cyst and left ovarian benign Brenner tumour. The patient was treated as per the carcinoma cervix protocol and is disease free at 1-year follow-up. To our knowledge this is the first report of such an occurrence. This occurrence cannot be related to any known hereditary syndromes, hence may be considered a chance association. Although rare, awareness of such an occurrence is important for the surgeon, radiologist and the surgical pathologist for proper diagnosis and management.

show abstract

Papillary Endometrial Adenocarcinoma with Cervical Dysplasia: Report of a Case and Review of Literature

Ramezani

Siami

Hosseini

et al. 2023

Asian Pac J Cancer Biol

View full text Add to dashboard Cite

Objective: Multifocality in gynecologic malignancies is a common phenomenon, however synchronous tumors may occur. Synchronous cancers are about 1.7% of gynecologic malignancies. Methods: A 57-year old female with chief complaint of vaginal bleeding was admitted. Endometrial curettage and cervical biopsy was done.Result: Pathologist reported: compatible with papillary adenocarcinoma, Grade II in endometrial sample and squamous epithelium with moderate dysplasia and tiny fragments of atypical glandular epithelium in endocervical samples. The patient refused for surgical excision of the lesion and insisted on to treat with conventional herbal medicine. Later Pap smear was done and pathologist reported: “High grade squamous intraepithelial lesion (HSIL) and atypical glandular cells, favor neoplastic in atrophic background”. Conclusion: In the case of gynecologic cancer be careful that it may accompany another gynecologic malignancy or premalignant lesion. The second lesion may occur synchronous or metachronous or may be metastatic. Many of the synchronous malignancies are presented in lower stages and have better prognosis than metastatic lesion. Thorough sampling and examination is important in correct diagnosis and treatment.

show abstract

Triple Synchronous Primary Neoplasms of the Cervix, Endometrium, and Ovary: A Rare Case Report and Summary of All the English PubMed-Indexed Literature

Cited by 6 publications

References 22 publications

Triple Synchronous Primary Malignancies of Ovary, Endometrium and Cervix – A Rare Case Report

Triple Synchronous Primary Malignancies of Ovary, Endometrium and Cervix – A Rare Case Report

Triple synchronous tumour of female genital tract: cervical squamous cell carcinoma, right ovarian dermoid cyst and left ovarian benign Brenner tumour

Papillary Endometrial Adenocarcinoma with Cervical Dysplasia: Report of a Case and Review of Literature

Contact Info

Product

Resources

About