Triploidy, partial mole and dispermy. An investigation of 12 cases

Abstract

Twelve triploid abortuses were investigated to determine the origin of the additional haploid set and were retrospectively examined for the development of partial hydatidiform mole. Eight out of ten suitable triploids were diagnosed as partial mole. Dispermy was indicated as the cause of triploidy in 6 informative cases of which 3 were also partial moles. However, one diandric triploid had no features of partial mole. The problem of maternal cell contamination in triploids and the difficulty of diagnosing partial moles on pathological grounds alone are discussed.

Diploid/triploid mixoploidy: A consequence of asymmetric zygotic segregation of parental genomes

“…The three studies with the largest sample size may be the least biased, as their samples were collected from series of consecutive abortions (Boué & Boué, ; Jacobs et al, ; Warburton, Byrne, & Canki, ). However, though the frequency values reported by Jacobs et al () (7.07%) and Warburton et al () (5.61%) were similar to those reported in smaller studies (4.5%) (Carr, ) and (7.32%) (Procter, Gray, & Watt, ), the frequency reported by Boué and Boué () (12.22%) was significantly higher, most likely due to the inclusion of earlier gestational losses.…”