Tris(indenyl)lanthanoid Complexes (Ln = La, Pr, Nd) Containing either (S)-(−)-Nicotine or Two Simpler Pyridine Bases

Guana, Jingwen; Fischer, R.

doi:10.1002/1099-0682(200109)2001:10<2497::aid-ejic2497>3.0.co;2-f

Cited by 18 publications

(3 citation statements)

References 20 publications

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“…But very little structural information on these compounds is available [4][5][6][7][8][9][10][11][12][13][14]. We have previously reported on crystal structure of the Cu(II) and Hg(ü) complexes of the type [Cu4Cu-Br)60(Nicotine) 4 ], [[HgX 2 (Nicotine)]"] (X = Br, I) [10][11][12]. The title compound is a neutral monomelic zinc(II) complex.…”

Section: Discussionmentioning

confidence: 99%

Crystal structure of [3-(2-(N-1H-methylpyrrolidinyl))pyridine]zinc(II) trichloride, Zn(C10H15N2)Cl3

Jiang¹,

Zhao²,

Wang³

2009

Zeitschrift Für Kristallographie - New Crystal Structures

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C10H15CI3N2Z11, orthorhombic, P2\2\h (no. 19), a = 8.9228(9) Â, fc = 11.611(1) Â, c = 13.877(1) Â, V = 1437.6 Â 3 , Ζ = 4, RgJF) = 0.025, wR^F) = 0.068, Γ =296 Κ. Source of materialZnCh (1.36 g, about 10 mmol) was added to dimethylacetamid (10 ml) solution, the mixture was stirred at room temperature for 5 min to obtain a colourless solution. Nicotine (2 ml, 2.02 g and 12.44 mmol) was then added dropwise, and an orange solution was formed. The solution was further stirred for about 20 min, after which a light orange precipitate was observed. The reaction mixture was filtered and the fíltrate was then transfered to a test tube and carefully layed by 10 ml i-PrOH. Colourless blockshaped crystals were obtained after 7 days. Experimental detailsThe C8 atom is disordered, with two distinct positions. The occupancy for the disordered parts was refined to be 0.45 : 0.55. Hydrogen atoms were positioned geometrically and refined using a DiscussionIt is well known that some metal complexes may retain or modulate the biological activity of the organic ligands in some drugs acting via chelation [2] or via the inhibition of metalloenzymes [3]. It is less known about the modification of activity of drugs when their ligating potential is utilized. The interaction of metal atoms, which play a vital role in a number of quite different biological processes, with therapeutically administered drugs is a subject of considerable interest. Several studies on the preparation and characterization of nicotine-metal complexes have been reported. But very little structural information on these compounds is available [4][5][6][7][8][9][10][11][12][13][14]. We have previously reported on crystal structure of the Cu(II) and Hg(ü) complexes of the type The title compound is a neutral monomelic zinc(II) complex. The zinc atom has a distorted tetrahedral coordination consisting of three chlorine atoms, and the fourth position occupied by the one nitrogen atom of the protonated nicotine molecule. The deviation from tetrahedral geometry is evidenced by the angles Nl-Znl-Cll of 104.06 (7) 0 and C12-Znl-Cll of 118.81(4)° and with Zn-CI bond distances between 2.2206(8) Â and 2.2898(8) Â. The behaviour of the two W-heterocycle-containing rings of nicotine is completely different. The pyridine ring is coordinated through Ν1 to a Ζη(Π) ion with NI-Znl bond distance of 2.071(2) À. The pyrrolidine ring is protonated at N2 and does not interact with metal ion, which is different from nicotinemercury(II), -silver(I) and nicotine-copper(II) complexes. In nicotine-copper(II) complexes,the pyrrolidine Ν atom is deprotonated. In nicotine-mercury(II) and nicotine-silver(I) compounds, the pyrrolline ring is connected through the deprotonated N2 atom to an another mercury(Π) and silver(I) atom and form a chain polymeric complexes [6,[11][12][13]. In addition, the absolut configurations of C6 and N2 can be given as S (Snicotine was used as a starting material). There are two kinds of non-typical intermolecular hydrogen bonds between the molecule, one is C...

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Section: Discussionmentioning

confidence: 99%

Crystal structure of [3-(2-(N-1H-methylpyrrolidinyl))pyridine]zinc(II) trichloride, Zn(C10H15N2)Cl3

Jiang¹,

Zhao²,

Wang³

2009

Zeitschrift Für Kristallographie - New Crystal Structures

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“…Several studies on the preparation and characterization of nicotine-metal complexes have been reported. But very little structural information on these compounds is available [4][5][6][7][8][9][10][11][12][13][14]. We have previously reported on crystal structure of the Cu(II) and Hg(II) complexes of the type [Cu 4 (m-Br) 6 O(Nicotine) 4 ], [[HgX 2 (Nicotine)] n ](X=Br, I) [10][11][12].…”

Section: Discussionmentioning

confidence: 99%

Crystal structure of [3-(2-(N-1H-methylpyrrolidinyl))pyridine]zinc(II) trichloride, Zn(C₁₀H₁₅N₂)Cl₃

Jiang¹,

Tang²,

Z³

et al. 2009

Zeitschrift Für Kristallographie - New Crystal Structures

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Source of materialZnCl 2 (1.36 g, about 10 mmol) was added to dimethylacetamid (10 ml) solution, the mixture was stirred at room temperature for 5 . min to obtain acolourless solution. Nicotine (2.ml, 2.02 gand 12.44 mmol) was then added dropwise, and an orange solution was formed. The solution was further stirred for about 20 min, after which alight orange precipitate was observed. The reaction mixture was filtered and the filtrate was then transfered to atest tube and carefully layed by 10 ml i-PrOH. Colourless blockshaped crystals were obtained after 7days. Experimental detailsThe C8 atom is disordered, with two distinct positions. The occupancy for the disordered parts was refined to be 0.45 :0.55. Hydrogen atoms were positioned geometrically and refined using a riding model with d(C-H) =0 .93 -0 .98 Å and U iso (H) =1 .2 U eq (C) [1.5 U eq (C) for the methyl group]. The Flack parameter is 0.000(12) for 1120 Friedel pairs [1]. DiscussionIt is well known that some metal complexes may retain or modulate the biological activity of the organic ligands in some drugs acting via chelation [2] or via the inhibition of metalloenzymes [3]. It is less known about the modification of activity of drugs when their ligating potential is utilized. The interaction of metal atoms, which play avital role in anumber of quite different biological processes, with therapeutically administered drugs is a subject of considerable interest. Several studies on the preparation and characterization of nicotine-metal complexes have been reported. But very little structural information on these compounds is available [4][5][6][7][8][9][10][11][12][13][14]. We have previously reported on crystal structure of the Cu(II) and Hg ( The title compound is aneutral monomeric zinc(II) complex. The zinc atom has adistorted tetrahedral coordination consisting of three chlorine atoms, and the fourth position occupied by the one nitrogen atom of the protonated nicotine molecule. The deviation from tetrahedral geometry is evidenced by the angles N1-Zn1-Cl1 of 104.06(7)°and Cl2-Zn1-Cl1 of 118.81(4)°and with Zn-Cl bond distances between 2.2206(8) . Å and 2.2898(8) .Å.The behaviour of the two N-heterocycle-containing rings of nicotine is completely different. The pyridine ring is coordinated through N1 to aZn(II) ion with N1-Zn1 bond distance of 2.071(2) Å .The pyrrolidine ring is protonated at N2 and does not interact with metal ion, which is different from nicotinemercury(II), -silver(I) and nicotine-copper(II) complexes. In nicotine-copper(II) complexes,the pyrrolidine Na tom is deprotonated. In nicotine-mercury(II) and nicotine-silver(I) compounds, the pyrrolline ring is connected through the deprotonated N2 atom to an another mercury(II) and silver(I) atom and form achain polymeric complexes [6,[11][12][13]. In addition, the absolut configurations of C6 and N2 can be given as S (Snicotine was used as astarting material). There are two kinds of non-typical intermolecular hydrogen bonds between the molecule, one is C4-H4···Cl1 with the donor···...

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“…To our knowledge, 2 represents the first tris(fluorenyl) rare-earth-metal complex. In stark contrast, tris(indenyl) derivatives (Ind) 3 Ln and (Ind) 3 Ln(Do) have been extensively investigated (Do = neutral donor molecules), 35 including the crystal structures of Ind 3 Ce(py) 36 and Ind 3 Ce(THF). 13 Moreover, the existence of 2 definitely rules out sterics to be the crucial factor for the formation of 1 Ce,Cl .…”

Section: ■ Introductionmentioning

confidence: 99%

Cerium Fluorenyl Complexes Including CC Coupling Reactions

et al. 2022

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The first structurally characterized fluorenyl (Flu) complexes of cerium are reported, bearing one, two, and three fluorenyl ligands. The reaction of CeX 3 (THF) x (X = Cl and I) with KFlu led to the half-sandwich complexes FluCeX 2 (THF) 3 . The chloride derivative was utilized in salt metathesis reactions, affording complexes FluCeR 2 (THF) x with R = OtBu, OSiMe 3 , OC 6 H 3 iPr 2 -2,6, Me 2 Pz, and Cp (x = 1 or 2; Me 2 Pz = 3,5dimethylpyrazolato, Cp = C 5 H 5 ). The mono(fluorenyl) complexes FluCeR 2 (THF) x are prone to ligand redistribution at ambient temperature, leading to the respective sandwich complexes Flu 2 CeR(THF). Utilization of K(2,10-tBu 2 Flu) (KFlu tBu ) afforded tris(fluorenyl) complex Flu tBu 3 Ce(THF) instead, showcasing two η 5 -and one η 1 -bound fluorenyl ligands. Treatment of FluCeCl 2 (THF) 3 with halogenating oxidants such as C 2 Cl 6 , I 2 , or TeBr 4 did not afford stable cerium(IV) species but mixtures of 9halogenidofluorene and 1,1′-bifluorene. Selective fluorenyl coupling reactions could be achieved for C 2 Cl 6 . Respective investigations with lanthanum and neodymium complexes support σ-bond metathesis as the main reaction path for C−C-bond formation.

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Tris(indenyl)lanthanoid Complexes (Ln = La, Pr, Nd) Containing either (S)-(−)-Nicotine or Two Simpler Pyridine Bases

Cited by 18 publications

References 20 publications

Crystal structure of [3-(2-(N-1H-methylpyrrolidinyl))pyridine]zinc(II) trichloride, Zn(C10H15N2)Cl3

Crystal structure of [3-(2-(N-1H-methylpyrrolidinyl))pyridine]zinc(II) trichloride, Zn(C10H15N2)Cl3

Crystal structure of [3-(2-(N-1H-methylpyrrolidinyl))pyridine]zinc(II) trichloride, Zn(C₁₀H₁₅N₂)Cl₃

Cerium Fluorenyl Complexes Including CC Coupling Reactions

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