1994
DOI: 10.1039/np9941100467
|View full text |Cite
|
Sign up to set email alerts
|

Triterpenoids

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1
1

Citation Types

0
7
0

Year Published

1995
1995
2020
2020

Publication Types

Select...
7
2
1

Relationship

0
10

Authors

Journals

citations
Cited by 14 publications
(7 citation statements)
references
References 100 publications
0
7
0
Order By: Relevance
“…As myricerone 3 was an apparent intermediate to 1 , we next focused on the synthesis of 3 from a readily available compound. Oleanolic acid ( 4 ) has a very close structure to 3 , and all that is required to convert 4 to 3 is oxidation of the 3-hydroxy to the 3-oxo group and hydroxylation of the methyl group at the 27-position. Barton and co-workers reported a synthesis of cincholic acid (3β-hydroxyolean-12-ene-27,28-dioic acid) three decades ago, which started from oleanolic acid ( 4 ) and introduced a hydroxy group at the 27-position by a photochemical reaction known as the Barton reaction …”
Section: Resultsmentioning
confidence: 99%
“…As myricerone 3 was an apparent intermediate to 1 , we next focused on the synthesis of 3 from a readily available compound. Oleanolic acid ( 4 ) has a very close structure to 3 , and all that is required to convert 4 to 3 is oxidation of the 3-hydroxy to the 3-oxo group and hydroxylation of the methyl group at the 27-position. Barton and co-workers reported a synthesis of cincholic acid (3β-hydroxyolean-12-ene-27,28-dioic acid) three decades ago, which started from oleanolic acid ( 4 ) and introduced a hydroxy group at the 27-position by a photochemical reaction known as the Barton reaction …”
Section: Resultsmentioning
confidence: 99%
“…Since 1985, Connolly and Hill have regularly reviewed the scientific literature dealing with triterpenoid characterization from natural resources. [239][240][241][242][243][244][245][246][247][248][249][250][251][252][253][254][255][256] Although numerous triterpenoids possessing various scaffolds have been reported, only a small portion of them were explored systematically for their pharmacological activities. Of those so explored, most showed only marginal potency in preliminary screening.…”
Section: Discussionmentioning
confidence: 99%
“…Of these, cycloartenol, eburicane, and several 3,4- seco -lanostane derivatives have all been identified as active compounds . Other interesting groups of tetracyclic triterpenoids and their degraded derivatives include the cucurbitacins (cucurbitanes), dammaranes, limonoids, and quassinoids. ,− Several lanostane derivatives have been identified as anti-inflammatory, antiviral, or anticancer agents; their effects on cell death, either through necrosis or apoptosis, have been partly implicated in their mechanism of action. ,, …”
Section: Introductionmentioning
confidence: 99%