2016
DOI: 10.1016/j.jelechem.2016.10.063
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Trithiane silver-nanoparticles-decorated polyaniline nanofibers as sensing element for electrochemical determination of Adenine and Guanine in DNA

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Cited by 26 publications
(6 citation statements)
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“…10 Moreover, an abnormal or incorrect alteration in the concentration of these bases in fluids and tissues can cause genetic mutations, decreased immunity, and various diseases, such as HIV infection, epilepsy and cancer. [11][12][13][14] Therefore, in order to assess the health status and achieve the earlier diagnosis of diseases, the concentration of nucleobases is considered to be crucial.…”
Section: àmentioning
confidence: 99%
“…10 Moreover, an abnormal or incorrect alteration in the concentration of these bases in fluids and tissues can cause genetic mutations, decreased immunity, and various diseases, such as HIV infection, epilepsy and cancer. [11][12][13][14] Therefore, in order to assess the health status and achieve the earlier diagnosis of diseases, the concentration of nucleobases is considered to be crucial.…”
Section: àmentioning
confidence: 99%
“…Therefore, simultaneous detection and analysis of the content of guanine and adenine is of great significance. Electrochemical method has been a good option owing to its low cost, simple operation process and high sensitivity . While the performance of the electrochemical method depends on the electrode, therefore, the ingenious designing of the electrode material will be the key .…”
Section: Introductionmentioning
confidence: 99%
“…Guanine and adenine, as important components of deoxyribonucleic acid, play an important role in cell energy transfer, enzyme catalytic signal transmission and other biological processes [1][2][3]. The abnormal changes of guanine and adenine not only can indicate the defects and mutations of the immune system in organism, but also may cause various diseases including HIV infection, epilepsy, cancer and AIDS [3][4][5][6]. Therefore, simultaneous detection and analysis of the content of guanine and adenine is of great significance.…”
Section: Introductionmentioning
confidence: 99%
“…Upon binding of a molecule onto a specially prepared metal surface or nanoparticle, such as silver or gold, the weak Raman activity can be greatly enhanced (by up to a factor of 10 14 ). This optical enhancement can even provide sufficient sensitivity for single-molecule detection. , These enhancement factors facilitate the acquisition of high-resolution vibrational spectra of biomolecules from very dilute aqueous solutions down to 10 –8 M. ,, As such, the detection and identification of nucleotides have become possible due to the unique SERS spectra of nucleobases. ,,, …”
Section: Introductionmentioning
confidence: 99%