2024
DOI: 10.1101/2024.10.15.618462
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TropD-Detector: A CRISPR/LbCas12a-Based system for rapid and sensitive screening ofTrypanosoma cruziin Chagas vectors and reservoirs

Luis A. Ortiz-Rodríguez,
Rafael Cabanzo,
Jeiczon Jaimes-Dueñez
et al.

Abstract: Chagas disease, also known as American Trypanosomiasis, is a zoonosis with global distribution caused by the parasite Trypanosoma cruzi, primarily transmitted through the feces of infected triatomines. The emergence of new cases in non-endemic areas highlights the importance of early pathogen detection in vectors and reservoirs to generate effective control strategies and establish preventive policies. The objective of this study was to design and validate a detection system of T. cruzi based on specific DNA c… Show more

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