Trophoblast and hypoblast in the monotreme, marsupial and eutherian mammal: evolution and origins

Selwood, Lynne; Johnson, Martin H.

doi:10.1002/bies.20360

Cited by 77 publications

(46 citation statements)

References 93 publications

(144 reference statements)

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“…This model is consistent with reports that the AVE arises partly from de novo gene expression in new cells and partly by early cells (Torres-Padilla et al, 2007). As in birds, there are differences in this topology and sequence of events among different mammals, including the rabbit (Viebahn et al, 1995), primates (Enders et al, 1990;Enders et al, 1986), pig (Hassoun et al, 2009) and monotremes (Kress and Selwood, 2006;Selwood and Johnson, 2006).…”

Section: Gene Expression In the Hypoblast And Vesupporting

confidence: 91%

The hypoblast (visceral endoderm): an evo-devo perspective

2012

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SummaryWhen amniotes appeared during evolution, embryos freed themselves from intracellular nutrition; development slowed, the mid-blastula transition was lost and maternal components became less important for polarity. Extra-embryonic tissues emerged to provide nutrition and other innovations. One such tissue, the hypoblast (visceral endoderm in mouse), acquired a role in fixing the body plan: it controls epiblast cell movements leading to primitive streak formation, generating bilateral symmetry. It also transiently induces expression of pre-neural markers in the epiblast, which also contributes to delay streak formation. After gastrulation, the hypoblast might protect prospective forebrain cells from caudalizing signals. These functions separate mesendodermal and neuroectodermal domains by protecting cells against being caught up in the movements of gastrulation.

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Section: Gene Expression In the Hypoblast And Vesupporting

confidence: 91%

The hypoblast (visceral endoderm): an evo-devo perspective

2012

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“…The development of novel techniques for lineage tracing and live imaging, and novel methods for the identification of new genes are a few examples. Investigation of early patterning mechanisms in non-mouse mammals has and will continue to illuminate the similarities and differences among mammalian developmental strategies (reviewed in Selwood and Johnson, 2006). In addition, stem cell lines from the first three lineages of the mouse and from the ICM of human embryos have not only provided an invaluable tool for developmental biologists, but they have emerged as a research model in their own right.…”

Section: Future Perspectivesmentioning

confidence: 99%

Cell and molecular regulation of the mouse blastocyst

Yamanaka

Ralston

Stephenson

et al. 2006

Developmental Dynamics

265

221

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Animals use diverse strategies to specify tissue lineages during development. A common strategy is to partition maternally supplied and localized lineage determinants into progenitor cells. The mouse embryo appears to use a different, more regulative strategy to specify the first three lineages: the epiblast (EPI: future embryo), the trophectoderm (TE: future placenta), and the primitive endoderm (PE: future yolk sac). These lineages are specified during two successive differentiation steps leading to formation of the blastocyst. Here, we review classic and contemporary models of early lineage specification in the mouse, and describe recent efforts to understand the molecular regulation of these events. We describe evidence that trophectoderm differentiation bears resemblance to the process of epithelialization and describe the importance of apical/basal protein complexes in regulating this process. Next, we present a revised model of PE specification, and describe evidence that PE cells in the inner cell mass sort out to occupy their ultimate position on the surface of the EPI. Finally, we describe factors that reinforce these lineages and three distinct stem cell types that can be isolated from them. Together, these mechanisms guide the differentiation of the first lineages of the mouse and thereby set up tissues that will be important for the first steps of embryonic body patterning. Developmental Dynamics 235:2301-2314, 2006.

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“…In reality, however, the mammalian egg is a highly specialized and restricted cell. It is programmed to undergo a stereotyped process of cleavage divisions that accomplishes the oocyte-to-embryo transition (Selwood and Johnson 2006). Developmental potential is unlocked through formation of the epiblast cells in the inner cell mass (ICM) of the blastocyst.…”

Section: Introductionmentioning

confidence: 99%

Pluripotency in the Embryo and in Culture

Nichols

Smith

2012

Cold Spring Harbor Perspectives in Biology

272

254

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SUMMARYSpecific cells within the early mammalian embryo have the capacity to generate all somatic lineages plus the germline. This property of pluripotency is confined to the epiblast, a transient tissue that persists for only a few days. In vitro, however, pluripotency can be maintained indefinitely through derivation of stem cell lines. Pluripotent stem cells established from the newly formed epiblast are known as embryonic stem cells (ESCs), whereas those generated from later stages are called postimplantation epiblast stem cells (EpiSCs). These different classes of pluripotent stem cell have distinct culture requirements and gene expression programs, likely reflecting the dynamic development of the epiblast in the embryo. In this chapter we review current understanding of how the epiblast forms and relate this to the properties of derivative stem cells. We discuss whether ESCs and EpiSCs are true counterparts of different phases of epiblast development or are culture-generated phenomena. We also consider the proposition that early epiblast cells and ESCs may represent a naïve ground state without any prespecification of lineage choice, whereas later epiblasts and EpiSCs may be primed in favor of particular fates.

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Trophoblast and hypoblast in the monotreme, marsupial and eutherian mammal: evolution and origins

Cited by 77 publications

References 93 publications

The hypoblast (visceral endoderm): an evo-devo perspective

The hypoblast (visceral endoderm): an evo-devo perspective

Cell and molecular regulation of the mouse blastocyst

Pluripotency in the Embryo and in Culture

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