As a contribution to understanding the genesis of tropical cyclones (TCs), we compared TC genesis processes simulated by the Seoul National University Atmosphere Model version 0 with a Unified Convection Scheme (SAM0) and the Community Atmosphere Model version 5 (CAM5) with those from the ERA-Interim reanalysis (ERA-Interim, hereafter ERAI) and best track observations. In contrast to previous studies that estimated the TC genesis potential using the Eulerian mean environmental conditions, we calculated the probability of a pre-existing weak cyclonic embryo vortex (EV) developing into a TC by analyzing changes in the environmental conditions along the EV trajectories. Our analysis indicates that the spatial distribution and annual cycles of TCs obtained from the SAM0 and ERAI are similar to those obtained from the best track observation data. With the exception of the mesoscale convective organization and associated variables, most environmental variables along the trajectories of DEVs (EVs developing into TCs) showed monotonic variations. When EVs were born, environmental conditions of DEVs were significantly different from those of nondeveloping EVs, allowing for the prediction of TC genesis. In general, TC genesis probability increased as the environment became more cyclonic, moist, unstable, and with a weaker wind shear. Rapidly strengthening EVs were more likely to develop into TCs. SAM0 and ERAI have the same combination of environmental variables with the best prediction skill for TC genesis—absolute vorticity at 850 hPa, column saturation deficit, sea surface temperature, vertical shear of horizontal winds between 200 and 850 hPa, and latitude—with similar sensitivities to individual environmental variables, indicating that SAM0 well simulates the observed TC genesis processes.