Tropical dermatology: Fungal tropical diseases

Lupi, Omar; Tyring, Stephen K.; McGinnis, Michael R.

doi:10.1016/j.jaad.2004.10.883

Cited by 207 publications

(189 citation statements)

References 123 publications

(223 reference statements)

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“…Disseminated histoplasmosis is a systemic mycosis that specifically affects the reticulohistiocytic system 8. It usually invades visceral organs (liver, spleen, pancreas, and intestines).…”

Section: Discussionmentioning

confidence: 99%

Disseminated histoplasmosis: a rare clinical phenotype with difficult diagnosis

Xiong

Fan

Kang

et al. 2017

Respirology Case Reports

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We describe a rare and interesting case of a 37‐year‐old man who presented with an intermittent fever, progressive cytopenia, and hepatosplenomegaly. Histopathological examination of a bone marrow smear revealed haemophagocytes and intracellular yeast‐like Histoplasma capsulatum (H. capsulatum); thus, we prolonged the blood culture duration to detect fungi, and H. capsulatum was detected in the peripheral blood. After the diagnosis of disseminated histoplasmosis, the patient was successfully treated with amphotericin B and symptomatic therapy. This is the first case in southwest China for which H. capsulatum was cultivated in peripheral blood, illustrating that the duration of specimen culture should be lengthened if a specific pathogen infection is suspected. Moreover, this case enriches our understanding of clinical manifestations of disseminated histoplasmosis.

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“…Disseminated histoplasmosis is a systemic mycosis that specifically affects the reticulohistiocytic system 8. It usually invades visceral organs (liver, spleen, pancreas, and intestines).…”

Section: Discussionmentioning

confidence: 99%

Disseminated histoplasmosis: a rare clinical phenotype with difficult diagnosis

Xiong

Fan

Kang

et al. 2017

Respirology Case Reports

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“…Extra cutaneous clinical presentations such as pulmonary, osteoarticular, ocular, and meningitis are rare. 7 The diagnosis is based on the clinical history and the isolation of the fungus via culture in medias such as Agar Sabouraud-dextrose or Agar dextrosepotato, incubated at 25°C. The growth of the colonies can be seen in 30 days.…”

Section: Discussionmentioning

confidence: 99%

“…With the use of special stainings like PAS, yeast aspects of S. schenckii like cigar-shaped structures and budding yeasts, as well as extracellular asteroid bodies, can be identified. 7,8 Serologic testes can be useful on the diagnosis of sporotrichosis, especially in atypical extra-cutaneous presentations. 4 In the cases presented here the likely source of infection was the infected domestic animal.…”

Section: Discussionmentioning

confidence: 99%

Ocorrência familiar de esporotricose zoonótica

Cordeiro

Bruno

Paula

et al. 2011

An. Bras. Dermatol.

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Abstract:Sporotrichosis is a suba cu te or chro nic myco sis cau sed by the dimor phic fun gus Sporothrix schenc kii which is ende mic in Brazil and is trans mit ted pri ma rily through trau ma tic ino cu la tion of its causa ti ve agent into the skin. The zoo no tic trans mis sion, espe cially from infec ted cats, has been demons trated in seve ral reports and case series. We pre sent simul ta neous occur ren ce of the disea se in three members of the same family by scrat ches from an infec ted domes tic cat. Two patients deve lo ped the lympho cuta neous form and one only deve lo ped the fixed cuta neous form. Two patients were suc cess fully trea ted with satu ra ted solu tion of potas sium iodi de; howe ver, the third case repor ted side effects and had his therapy subs ti tu ted for itra co na zo le, with reso lu tion of his lesions. Keywords: Cats; Disease trans mis sion, infec tious; Potassium iodi de; Sporotrichosis Resumo: A espo ro tri co se é mico se suba gu da ou crô ni ca, cau sa da pelo fungo dimór fi co Sporothrix schenckii, endê mi ca no Brasil e trans mi ti da prin ci pal men te atra vés da ino cu la ção trau má ti ca de seu agen te cau sal na pele. A trans mis são zoo nó ti ca, espe cial men te por gatos infec ta dos, tem sido demons tra da em diver sos rela tos e séries de casos. Nós des cre ve mos a ocor rên cia simul tâ nea da doen ça em três mem bros de uma mesma famí lia atra vés da arra nha du ra por gato domés ti co infec ta do. Dois pacien tes desen vol ve ram a forma cutâ nea-lin fá ti ca e ape nas um desen vol veu a forma cutâ nea fixa. Dois pacien tes foram tra ta dos com sucesso, com solu ção satu ra da de iode to de potás sio; entre tan to, o ter cei ro caso apre sen tou efei tos cola te rais e teve seu tra ta men to subs ti tuí do por itra co na zol, com reso lu ção de suas lesões. Palavras-chave: Esporotricose; Gatos; Iodeto de potás sio; Transmissão de doen ça infec cio sa

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“…1. Among the diseases caused by different etiological agents of fungal origin, chromoblastomycosis and Jorge Lobo's disease assume a particular importance in the Brazilian Amazon region due to their incidence related to the characteristics of the regional environment [1,2,3,4] . Jorge Lobo's disease, or lacaziosis, is a chronic mycosis caused by Lacazia loboi [5,6] , which is characterized by keloidal cutaneous lesions mainly located in the auricle and lower limbs of humans [2,3] .…”

Section: Introductionmentioning

confidence: 99%

“…The symptoms are discrete. Nodules, papules or ulcerations present separately or in groups may ulcerate, discharging a caseous secretion and leading to the emergence of verruciform masses with a cauliflower-like appearance [4] . The lesions are generally found in [4,8] .…”

Section: Introductionmentioning

confidence: 99%

An Unusual Association between Chromoblastomycosis and Jorge Loboâ€™s Disease in the Same Patient from the Amazon Region

Costa¹,

Silva²,

Almeida³

et al. 2008

American J. of Agricultural and Biological Sciences

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Abstract:A clinical case of co-infection Cladophialophora sp. and Lacazia loboi is described and in a same patient with an 18-year history of verrucous plaques and parakeloidal nodular lesions. A 50-yearold man, a laborer, living in the Anajás city, Para, Brazil (rural Amazon region), was seen at the Evandro Chagas Institute's ambulatory. Histopathological analysis revealed intense hyperplasia and hyperkeratosis of the epidermis, sometimes showing well-circumscribed areas of an intraepidermal suppurative content intermingled with round and brownish structures. The papillary and reticular dermis was characterized by fibrosis and a granulomatous reaction consisting of lymphocytes, histiocytes and giant cells permeated by suppurative inflammatory foci and multiple round fungal structures mainly arranged amidst a neutrophilic inflammatory infiltrate. The clinical material collected from the lesion was submitted to direct mycological examination using 20% KOH solution and lactophenol cotton blue, which revealed the presence of yeast-like cells with a double membrane arranged in groups, a characteristic of Lacazia loboi, as well as sclerotic cells characteristic of chromoblastomycosis. Culture of the specimen on Mycosel agar and microculture on potato agar showed the typical morphology of Cladophialophora sp. The association of these two fungi causing lesions and inducing long-term disease may indicate a similarity in the characteristics of the habitat of these agents in the Amazon region.

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Tropical dermatology: Fungal tropical diseases

Cited by 207 publications

References 123 publications

Disseminated histoplasmosis: a rare clinical phenotype with difficult diagnosis

Disseminated histoplasmosis: a rare clinical phenotype with difficult diagnosis

Ocorrência familiar de esporotricose zoonótica

An Unusual Association between Chromoblastomycosis and Jorge Loboâ€™s Disease in the Same Patient from the Amazon Region

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