Troublesome tumours. 1: Adnexal tumours of the skin.

Cotton, D. W. K.

doi:10.1136/jcp.44.7.543

Cited by 35 publications

(29 citation statements)

References 16 publications

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“…Tumours of the hair follicle show differentiation towards many of the normal follicular elements and are generally named accordingly. 13 Most of the skin adnexal tumours in our study 30 cases (58.82%) were <1.5 centimeters in maximum dimensions, which was also seen in Pujani M et al Rarely size may exceed 1.5cm, one case of Eccrine spiradenoma size was 4cm, and one case of Trichilemmal cyst was 6cm (Table 7). 14 Most of skin adnexal tumours are benign and remain localized to site.…”

supporting

confidence: 50%

Prospective study of skin adnexal tumours for a period of two years in a tertiary care hospital

Sanapala¹,

Suvvari²,

Seeram³

et al. 2017

Int J Res Med Sci

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Background: Skin adnexal tumours are rare tumours with complex histological patterns and variations and difficult to diagnose by histopathology only, so clinical history and presentation is necessary. The objective of the study was to correlate with age, sex, location, type of differentiation of adnexal tumours in our pathology department.Methods: The present study was a prospective study done in the department of pathology in Andhra medical college, King George Hospital, Visakhapatnam. A total of 51 cases were included in this study from January 2015 to December 2016. Specimens were formalin fixed and after adequately processing the sections were stained routinely with hematoxylin and eosin stain and properly evaluated for histopathological examination.Results: Out of these 51 cases, 88.24% (45 cases) were benign, and 11.76% (6 cases) were malignant tumours. Hair follicle differentiation were most common (35.3%) followed by sebaceous gland differentiation (31.37%) and sweat gland differentiation (29.41%).Conclusions: Benign adnexal tumours were most common than malignant tumours. Skin adnexal tumours are clinically often misdiagnosed, so histopathological examination remains gold standard for their correct diagnosis.

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supporting

confidence: 50%

Prospective study of skin adnexal tumours for a period of two years in a tertiary care hospital

Sanapala¹,

Suvvari²,

Seeram³

et al. 2017

Int J Res Med Sci

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“…1 Afterwards, Mehregan 2 divided them in 1985 by simplifying to three subgroups which are called hyperplasia, adenoma and epithelioma. Ackerman et al criticised the classifications, used in eight textbooks of dermatopathology in 2001.…”

Section: Introductionmentioning

confidence: 99%

“…3,4 Tumors of cutaneous appandages originating from hair follicle was seperated into two main subgroups as benign tumors and malignant tumors according to 2003 Classification of World Health Organization (WHO). 1 Trichoadenoma (TA) is firstly determined by Nikolowski 5 in 1958 and is a rare tumor which is usually seen as a nodular lesion on the face and buttocks. 6,7 Trichofolliculoma (TF) is follicularly differentiated hamartomas mostly appearing during adulthood 8 without sex special tendency.…”

Section: Introductionmentioning

confidence: 99%

Histopathological Characteristics may not be Useful in the Differential Diagnosis Between Basal Cell Carcinoma and Benign Tumors of Cutaneous Appandages Originating from Hair Follicle

Şengül¹

2011

UHOD

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Differential diagnosis between benign tumors of cutaneous appandages originating from hair follicle (BTCOHF) (trichoadenoma [TA], trichofolliculoma [TF], trichoepithelioma [TE] and trichoblastoma [TB]) and basal cell carcinoma (BCC) have been tedious for the pathologists, especially in the presence of small specimens to date. Thirty cases of BTCOHF and 30 cases of BCC were retrieved from the archives, deposited from 2004 to 2008. Age, sex, localisation and histopathological characters such as ulceration, pigmentation, inflammation, and cyst formation were comparatively evaluated between both groups and each subgroups. No significant diference was detetected between two groups in the rate of the age, sex and the histopathology. Besides, histopathological characters were not significant for the subgroups of BCC. However, ulceration was observed in TE (Of 21 cases 5, [23.8%]) and TB (All the 5 cases, [100%]), but not in TA and TF which are the subgroups of BTCOHF and the difference was significant (p= 0,005). But, pigmentation, inflammation and cyst formation were not significant among the subgroups of both groups. We can conclude that BCC and BTCOHF may not be discriminated concerning age, sex and histopathological characters including ulceration, pigmentation, inflammation, and cyst formation. Secondly, one may not make the differential diagnosis easily even between the subgroups of each group via evaluating the histopathological characters, so that might create some life-threatening unwelcome outcomes. Keywords: Basal cell carcinoma, Pigmentation, Inflammation, Histopathology ÖZET Histopatolojik karakterler Bazal Hücreli Karsinoma ile K›l Follikülünden Köken Alan Benign Deri Eki Tümörlerinin Ay›r›c› Tan›s›nda Yararl› OlamayabilirTrikoadenoma, trikofolliküloma, trikoepitelyoma ve trikoblastoman›n bazal hücreli karsinomadan ay›r›c› tan›s›, bugüne kadar özellikle küçük spesimenlerde patologlar için can s›k›c› ve usand›r›c› olmaya devam edegelmifltir. Otuz k›l follikülünden köken alan benign deri eki tümörleri olgusu ve 30 bazal hücreli karsinoma olgusu, 2004 -2008 y›llar› aras›nda depoland›¤› arflivden yeniden edinildi. Yafl, cinsiyet, lokalizasyon ve ülserasyon, pigmentasyon, inflamasyon ve kist formasyonu gibi histopatolojik karekterler her iki grup ve her subgrup aras›nda karfl›laflt›rmal› olarak de¤erlendirildi. Yafl, cinsiyet, lokalizasyon ve histopatoloji aç›s›ndan iki grup aras›nda anlaml› fark saptanmad›. Ayr›ca, histopatolojik karekterler bazal hücreli karsinoman›n subgruplar› için anlaml› de¤ildi. Bununla birlikte; ülse-rasyon, k›l follikülünden köken alan benign deri eki tümörlerinin subgruplar› olan trikoepitelyoma (21 olgunun 5'inde [%23.8]) ve trikoblastomada (5 olgunun tümünde [%100]) izlendi, ancak trikoadenoma ve trikofollikülomada izlenmedi ve bu fark anlaml› bulundu (p= 0.005). Pigmentasyon, inflamasyon ve kist formasyonu her iki grubun subgruplar› aras›nda anlaml› de¤ildi.

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“…In the present study, we have followed the WHO classification of skin tumors, 2006. 1 Atypia, more nuclear than cellularity, is regarded as the most important histologic trait favouring malignancy. This term refers to nuclei that are larger, darker, variably sized, irregularly outlined, have coarse chromatin, nucleoli and abnormal mitoses.…”

Section: Discussionmentioning

confidence: 99%

“…1 In 1874, Sir James Paget first described few cases of eczematous lesions of the nipple and areola and noted that mammary cancer developed in all patients within two years. MPD occurs almost exclusively in women.…”

Section: Discussionmentioning

confidence: 99%

Spectrum of malignant skin adnexal tumors - a single institution study of 17 cases with clinicopathological correlation

et al. 2015

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Troublesome tumours. 1: Adnexal tumours of the skin.

Cited by 35 publications

References 16 publications

Prospective study of skin adnexal tumours for a period of two years in a tertiary care hospital

Prospective study of skin adnexal tumours for a period of two years in a tertiary care hospital

Histopathological Characteristics may not be Useful in the Differential Diagnosis Between Basal Cell Carcinoma and Benign Tumors of Cutaneous Appandages Originating from Hair Follicle

Spectrum of malignant skin adnexal tumors - a single institution study of 17 cases with clinicopathological correlation

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