Trousseau's sign in the left internal jugular vein in gastric cancer

Ethiraj, Dillibabu; Indiran, Venkatraman; Kannan, K.; Madhuraimuthu, Prabakaran

doi:10.4103/ijc.ijc_321_18

Cited by 2 publications

(2 citation statements)

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“…Based on the present experience with the overall deceiving long term survival of the studied population, the appearance of a cancerrelated cervical mass can be considered a sign of dismal prognosis of gastric carcinoma. Cervical resection, therefore, is not focused on prolonging survival but simply on improving the quality of life, despite a light enhancement of transitory postoperative complications compared to anticoagulation and treatment of the primary tumor alone (3)(4)(5)(6). Cervical resection may help in the diagnosis of an actually still unknown neoplasm, as macroscopic evidence of the primary tumor may not be evident for 2 to 12 months from the initial presentation of phlebitis-related mass and swelling (11,12).…”

Section: Discussionmentioning

confidence: 99%

“…Involvement of a distal site as first clinical sign of gastric cancer, although quite rare, is known and includes migratory trombophlebitis or Trousseau's syndrome (1) and metastasis to supraclavicular Virchow's node, known as Troisier's sign (2). The appearance of a cervical mass and swelling due to thrombosis if the internal jugular veinn (IJV) related to gastric carcinoma, has recently been the subject of isolated case reports (3)(4)(5)(6) and treated with anticoagulation. The prognostic value of this sign is not well defined.…”

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confidence: 99%

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Resection for Internal Jugular Vein Thrombosis and Cervical Lymph Nodes' Involvement from Gastric Cancer

et al. 2020

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Background/Aim: Thrombosis internal jugular vein (IJV) with cervical adenopathy, as first manifestation of gastric cancer is rare. We aimed to compare resection of the cervical mass followed by gastrectomy with gastrectomy alone. Patients and Methods: Nine patients presenting thrombosis of the IJV for gastric carcinoma were divided into two groups. Patients in group A (n=3) underwent anticoagulation treatment, gastrectomy and adjuvant treatment. Patients in group B (n=6) underwent resection of the cervical mass and internal jugular vein (radical neck dissection), and then gastrectomy and adjuvant treatment. Results: Median survival was 15.3 months in group A (range=11-19 months) and 31.2 months in group B (range=7-44 months) (p=0.11). Late cervical recurrence/ complications occurred in 2 patients in group A and none in group B (p=0.02). Conclusion: Resection of thrombosed IJV and satellite lymph nodes, due to a primary gastric cancer may contribute to diagnosis of the disease, limit pulmonary embolic complications and improve quality of life.

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Section: Discussionmentioning

confidence: 99%

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Resection for Internal Jugular Vein Thrombosis and Cervical Lymph Nodes' Involvement from Gastric Cancer

et al. 2020

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Internal Jugular Vein Thrombosis: Etiology, Symptomatology, Diagnosis and Current Treatment

et al. 2021

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(1) Background: internal jugular vein thrombosis (IJVthr) is a potentially life-threating disease but no comprehensive reviews on etiology, symptomatology, diagnosis and current treatment guidelines are yet available; (2) Methods: we prospectively developed a protocol that defined objectives, search strategy for study identification, criteria for study selection, data extraction, study outcomes, and statistical methodology, according to the PRISMA standard. We performed a computerized search of English-language publications listed in the various electronic databases. We also retrieved relevant reports from other sources, especially by the means of hand search in the Glauco Bassi Library of the University of Ferrara; (3) Results: using the predefined search strategy, we retrieved and screened 1490 titles. Data from randomized control trials were few and limited to the central vein catheterization and to the IJVthr anticoagulation treatment. Systematic reviews were found just for Lemierre syndrome, the risk of pulmonary embolism, and the IJVthr following catheterization. The majority of the information required in our pre-defined objectives comes from perspectives observational studies and case reports. The methodological quality of the included studies was from moderate to good. After title and abstract evaluation, 1251 papers were excluded, leaving 239 manuscripts available. Finally, just 123 studies were eligible for inclusion. We found out the description of 30 different signs, symptoms, and blood biomarkers related to this condition, as well as 24 different reported causes of IJVthr. (4) Conclusions: IJVthr is often an underestimated clinical problem despite being one of the major sources of pulmonary embolism as well as a potential cause of stroke in the case of the upward propagation of the thrombus. More common symptoms are neck pain and headache, whereas swelling, erythema and the palpable cord sign beneath the sternocleidomastoid muscle, frequently associated with fever, are the most reported clinical signs. An ultrasound of the neck, even limited to the simple and rapid assessment of the compression maneuver, is a quick, economic, cost-effective, noninvasive tool. High quality studies are currently lacking.

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Trousseau's sign in the left internal jugular vein in gastric cancer

Cited by 2 publications

References 6 publications

Resection for Internal Jugular Vein Thrombosis and Cervical Lymph Nodes' Involvement from Gastric Cancer

Resection for Internal Jugular Vein Thrombosis and Cervical Lymph Nodes' Involvement from Gastric Cancer

Internal Jugular Vein Thrombosis: Etiology, Symptomatology, Diagnosis and Current Treatment

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