Trout Hepatoma — A Preliminary Report

Rucker, Robert R.; Yasutake, W. T.; Wolf, Harold

doi:10.1577/1548-8659(1961)23[3:thapr]2.0.co;2

Cited by 38 publications

(3 citation statements)

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“…Bioassays with the lipid fraction showed results comparable with those reported by Sinnhuber (1967) and the histopathology of selected suspect samples reported by Ashley (1967) and Wales (1967). These data also confirmed, extended and rationalized the reports by Rucker et al (1961) and Wolf and Jackson (1963) and of the nutritionally induced. hepatoma in rainbow trout reported by Yasu take and Rucker (1967).…”

Section: Chronic Aflatoxicosis and Hepatomagensissupporting

confidence: 90%

Aflatoxicosis and Adventitious Toxins for Fish

Halver

1976

Fish Pathol.

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Section: Chronic Aflatoxicosis and Hepatomagensissupporting

confidence: 90%

Aflatoxicosis and Adventitious Toxins for Fish

Halver

1976

Fish Pathol.

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“…As a result of cell kernel injury, there appear mutations that are triggers of oncological diseases [9]. Among all cells of the organism, liver ones are injured mostly, because hepatomas are typical for aflatoxicosis [10]. Clinical sings at the severe clinical course of aflatoxicosis are not expressed and include refusal of food and unexpected death.…”

Section: Introductionmentioning

confidence: 99%

Aflatoxicosis of crucians: experimental treatment and biological value of fish

Петров

Pidlubniy

2021

Eureka: LS

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The aim of this study was to investigate a possibility to decrease a toxic influence of aflatoxin on the fish organism and veterinary-sanitary evaluation of fish, fed by a pure fodder, aflatoxin and ketoconazole+aflatoxin. Fish aflatoxicoses cause essential losses at fish growing using industrial production technologies. It is characterized by decreasing weight gains and increasing kill of commodity fish, worsening fodder conversion. Farmers often use fodders of own production, without conducting laboratory studies, and don’t know about aflatoxins. At the same time because of different reasons, first of all economic ones, they don’t use adsorbents for decreasing the negative influence of aflatoxins on the fish organism. Their use doesn’t guarantee 100 % fish resistance to micotoxicoses and correspondingly product safety for a consumer. Fish, received aflatoxins with food, is dangerous as a food product for humans and animals. Aflatoxins are very stable in the environment, so even thermal processing doesn’t exceed risk of aflatoxin contamination. The article presents a possibility of effective treatment of fish at aflatoxicosis. It is known, that aflatoxin beyond cells is not dangerous. Its activation takes place within a cell by the enzyme system cytochrome Р-450, forming an epoxide, in which result the aflatoxin inclusion complex with DNA forms in the kernel. The veterinary preparation “Ketoconazole” inhibits cytochrome enzymes Р-450, so aflatoxin activation within a cell doesn’t take place, epoxides don’t form, DNA cells are not injured, aflatoxicosis doesn’t develop in fish that has been proved experimentally. The veterinary-sanitary mark of fish, treated for aflatoxicosis, is satisfactory. The importance of this study is in fact that for today there is no developed effective method of fish aflatoxicosis treatment. An influence of aflatoxin on the crucian organism has not been studied experimentally

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“…Aflatoxins were first isolated about 40 years ago after outbreaks of disease and death in turkeys (Williams et al, 2004) and cancer in rainbow trout (Rucker et al, 2002;Williams et al, 2004) fed with rations formulated from peanut and cottonseed meals. These toxins are secondary metabolites produced under certain conditions of temperature, pH and humidity predominantly by Aspergillus flavus and Aspergillus parasiticus fungi species (Bhatnagar et al, 2006).…”

Section: Introductionmentioning

confidence: 99%

International Symposium on Occupational Safety and Hygiene: Proceedings Book of the SHO2013

2013

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A Sociedade Portuguesa de Segurança e Higiene Ocupacionais realiza, em 14 e 15 de Fevereiro de 2013, a 9ª edição do Colóquio Internacional de Segurança e Higiene Ocupacionais - SHO 2013. Tal como nos seis últimos anos, o evento tem lugar na Escola de Engenharia da Universidade do Minho, em Guimarães. A edição de 2013 abrange as temáticas da Ergonomia e do Ambiente Físico, dos Riscos Químicos e Biológicos, da Segurança contra Incêndio e da Gestão da Prevenção, que são objecto de sessões plenárias, decorrendo ainda várias sessões paralelas de comunicações livres nas mais de 25 áreas temáticas previstas para o evento, bem como várias sessões com apresentação de posters.

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Trout Hepatoma — A Preliminary Report

Cited by 38 publications

References 0 publications

Aflatoxicosis and Adventitious Toxins for Fish

Aflatoxicosis and Adventitious Toxins for Fish

Aflatoxicosis of crucians: experimental treatment and biological value of fish

International Symposium on Occupational Safety and Hygiene: Proceedings Book of the SHO2013

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