A 36 year old woman booked for her eighth pregnancy at 17 weeks of gestation. She had previously had four first trimester miscarriages (three requiring evacuation of the uterus), two normal vaginal deliveries at term, and in her last pregnancy, an emergency lower segment caesarean section at 37 weeks of gestation for antepartum haemorrhage secondary to a major degree of placenta praevia. At her booking visit the mode of delivery was discussed, and a decision was made to allow a trial of vaginal delivery.There were no antenatal complications until 41 weeks of gestation. At that time, the blood pressure was found to be 160/100 mmHg (booking blood pressure 130/70 mmHg) without proteinuria or generalised oedema. Abdominal palpation revealed an appropriately sized fetus, with the head two-fifths palpable. A vaginal examination was performed and the Bishop score was 3. Arrangements were made for prostaglandin induction of labour the next day.At 09:OO she was admitted to the antenatal ward and 1 mg of prostaglandin gel (UpJohn Ltd, Crawley, UK) was inserted into the posterior fornix. Subsequent cardiotocography was normal. After 6 hours the patient was reviewed. She complained of mild, irregular contractions, and vaginal examination revealed the cervix to be 1 cm dilated (Bishop score 5). A further 1 mg of prostaglandin was given. Two hours later contractions had become strong and regular with a frequency of four to five in 10 minutes. A vaginal examination showed the cervix to be 4 cm dilated, cephalic presentation 2 cm above the ischial spines with bulging membranes. Arrangements were made for immediate transfer to the delivery suite during which she complained of increasing and persistent abdominal pain. On arrival at the delivery suite she was noted to be pale, tachycardic and hypotensive. Abdominal palpation revealed increasing abdominal distension and neither fetal parts nor the fundal height could be identified. On vaginal examination the presenting part was no longer palpable, and the fetal heart was absent. An immediate laparotomy through a midline incision was performed, and a 3 L haemoperitoneum was found. The uterus had ruptured posteriorly, the male fetus was lying free in the peritoneal cavity and was stillborn. The lower segment caesarean section scar remained intact. The damage was considered to be too extensive for repair and a total abdominal hysterectomy was performed. Clotting studies remained normal throughout, and she required a total of 6 units of blood. She made an uncomplicated post-operative recovery, and was discharged on the sixth post-operative day.
DiscussionUterine rupture is fortunately a rare event. It is seen most commonly where there has been a previous lower segment scar, and it is a rare event in developed countries to see rupture of an unscarred uterus. We know of only two cases of uterine rupture following vaginal prostaglandin E, (PGE,) induction of labour (without oxytocin) in women with a previous caesarean section scar described in the literature'. In both the rupture involved...