2006
DOI: 10.1007/s00423-006-0092-y
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True smooth muscle neoplasms of the gastrointestinal tract: morphological spectrum and classification in a series of 85 cases from a single institute

Abstract: Smooth muscle neoplasms are the second most common mesenchymal neoplasms in the GI tract after GISTs. They may arise either from the muscularis mucosae or proper muscle layer forming polypoid and intramural lesions, respectively. Polypoid leiomyomas are more common in the rectosigmoid, while intramural ones mainly arise in the vicinity of the oesophagogastric junction. Polypoid leiomyomas are sufficiently treated by endoscopic resection, and local surgical excision is the treatment of choice for intramural lei… Show more

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Cited by 85 publications
(81 citation statements)
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“…Within the gastrointestinal tract, leiomyomas predominately occur in the esophagus (1). Gastric leiomyomas are benign submucosal tumors composed of smooth muscle cells, and account for 2.5% of all gastric neoplasms (2,3). Leiomyomas are most frequently encountered in patients aged 50-70 years and bear no gender predilection (4).…”
Section: Introductionmentioning
confidence: 99%
“…Within the gastrointestinal tract, leiomyomas predominately occur in the esophagus (1). Gastric leiomyomas are benign submucosal tumors composed of smooth muscle cells, and account for 2.5% of all gastric neoplasms (2,3). Leiomyomas are most frequently encountered in patients aged 50-70 years and bear no gender predilection (4).…”
Section: Introductionmentioning
confidence: 99%
“…육종은 소장의 악성종양 중 1.2% 이내로 유암종, 선암종, 림프종, 위장관기질종양에 이 어 빈도 순으로 5번째인 매우 드문 질환이며 [2], 소장의 평활 근육종은 전체 위장관 악성간엽종양의 약 1%를 차지하고 있다 [3]. 평활근육종은 소장에서 발생하는 육종의 한 형태로 평활근 세포의 점막근, 고유근층에서 유래하며 50대 남성에 게서 더 많이 발생한다 [4].…”
Section: 서 론unclassified
“…여러 질환 들을 감별하기 위해 시행한 면역조직화학검사에서 vimentin과 desmin에 미만성으로 세포질에 강한 양성반응을 나타내었고 (Fig. 7), smooth muscle actin과 caldesmon에는 국소적인 세포에서 양성반응을 보였으며, CD117, CD34, DOG-1, HMB45, CD31, CD99, pan cytokeratin, cytokera- 에 이어 빈도 순으로 5위를 차지하는 매우 드문 질환이다 [3].…”
Section: 을 가진 종양세포를 관찰할 수 있었으며 50 Hpf에서 40개unclassified
“…Although we cannot rule out the possibility that colorectal leiomyomas of the muscularis mucosae progress to leiomyosarcomas, there is no evidence of malignant transformation. 14,17 For GI submucosal tumors, complete surgical resection is still considered the most definitive treatment. However, the choice of treatment for colonic submucosal tumors is controversial.…”
Section: In a Large Series Involving Two Referral Centers In The Unitedmentioning
confidence: 99%
“…2,[4][5][6][7][8][9][10][11][12][13] Since screening colonoscopy for colorectal cancers became widely available, the detection of small polypoid leiomyomas by colonoscopy has increased. 14 In the present study, we evaluated clinicopatho-logical characteristics of colorectal polypoid leiomyomas and the efficacy and outcome of endoscopic removal of these lesions.…”
Section: Introductionmentioning
confidence: 99%