Background: While the share of bioenergy in the overall energy supply has increased over the last decade, its social acceptance is fragile, mainly due to concerns about negative sustainability impacts. In this paper, we will investigate to what extent the extension of bioenergy towards 'smart' or 'cascaded' biomass use enhances a project's social acceptance. Smart use involves the prioritised use of biomass for food and materials. Methods: We adopt an explorative single case study approach to investigate issues of social acceptance. Our case is the Biobased Economy Park at Cuijk, in The Netherlands. The central element in this project is the revival of an existing but off-line biopower plant. For the power company involved, the integration of biopower into a broader smart use scheme, involving several new business partners, is a strategy to make the exploitation of the plant profitable again. For the data collection, we used interviews, as well as information provided by members of our expert panel, in addition to information collected from websites and provided at a bioeconomy event. The data was analysed by taking existing conceptual work on the social acceptance of renewable energy innovation as a guide. Results: We found that issues of social acceptance changed rather than diminished when entrepreneurs extended a project's focus from biopower to smart biomass use. This change can be observed in relation to all three conceptual categories: market acceptance, sociopolitical acceptance and community acceptance. Conclusions: We conclude that the extension from bioenergy towards smart biomass use does not necessarily enhance a project's social acceptance. Compared to the social acceptance of renewable energy innovation, the social acceptance of smart biomass use is fuzzier, more open to recursive patterns and more dependent upon inter-firm trust. Importantly, embracing the principle of smart biomass use instigates the question of how biomass use can be optimised-either with or without purposes related to energy. We suggest further comparative case study research into the social acceptance dynamics of smart biomass use, for which we identify the following variables as relevant: the type of bioenergy, the sector that takes the initiative, the greenfield character of the project and the complexity of the smart use scheme.