2024
DOI: 10.1097/qai.0000000000003454
|View full text |Cite
|
Sign up to set email alerts
|

Tryptophan–Kynurenine Pathway Activation and Cognition in Virally Suppressed Women With HIV

Eran Frank Shorer,
Raha M. Dastgheyb,
Audrey L. French
et al.

Abstract: Background: Immune and cognitive dysfunction persists even in virally suppressed women with HIV (VS-WWH). Since inflammation and HIV proteins induce the enzyme IDO (indoleamine 2, 3-dioxygenase), converting tryptophan (T) to kynurenine (K) while producing downstream neurotoxic metabolites, we investigated IDO activation (KT ratio) in relation to cognition in VS-WWH and demographically similar women without HIV (WWoH). Methods: 99 VS-WWH on stable antire… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

0
0
0

Publication Types

Select...

Relationship

0
0

Authors

Journals

citations
Cited by 0 publications
references
References 65 publications
0
0
0
Order By: Relevance

No citations

Set email alert for when this publication receives citations?