TSNM Procedure Guideline for PET Brain Imaging using F-18 FDG

Yaylalı, Olga; Koç, Pınar; Aydın, Funda; Salancı, Bilge Volkan; Kaya, Meryem; Akdemir, Ozgur; Çakır, Tansel

doi:10.4274/nts.2015.012

Cited by 1 publication

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“…The results were interpreted with visual inspection, regional glucose metabolic rates and zscores. A z-score of +2 or above indicated hypermetabolism, while a z-score of -2 or below indicated hypometabolism in a particular region (6)(7)(8). Figure 1 shows the F-18 FDG uptake rates, z-scores, and color-coded images of a patient participating in the study, as an example.…”

Section: Data Processingmentioning

confidence: 99%

Posterior cingulate cortex hyperactivity in conversion disorder: a PET/MRI study

Tatlı,

Araz,

Özkan

et al. 2024

Front. Psychiatry

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IntroductionSeveral neuroimaging studies have been conducted to demonstrate the specific structural and functional brain correlations of conversion disorder. Although the findings of neuroimaging studies are not consistent, when evaluated as a whole, they suggest the presence of significant brain abnormalities. The aim of this study is to investigate brain metabolic activity through F-18 fluorodeoxyglucose PET/MRI in order to shed light on the neural correlates of conversion disorder.Methods20 patients diagnosed with conversion disorder were included in the study. Hamilton Depression and Anxiety Rating Scales, Somatosensory Amplification Scale and Somatoform Dissociation Scale were administered. Then, brain F-18 FDG-PET/MRI was performed..ResultsHypermetabolism was found in posterior cingulate R, while glucose metabolisms of other brain regions were observed to be within the normal limits. When compared with the control group, statistically significant differences in z-scores were observed among all brain regions except for parietal superior R and cerebellum. No correlation was observed between the metabolisms of the left ACC and left medial PFC; left ACC and left temporal lateral cortex; cerebellum and left parietal inferior cortex despite the presence of positive correlations between these regions in the opposite hemisphere.DiscussionResults of the study suggest a potential involvement of the DMN which is associated with arousal and self-referential processing as well as regions associated with motor intention and self-agency.

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Section: Data Processingmentioning

confidence: 99%