Through silicon via (TSV) based 3D integrated circuits have inspired a novel design paradigm which explores the vertical dimension, in order to alleviate the performance and power limitations associated with long interconnects in 2D circuits. TSVs enable vertical interconnects across stacked and thinned dies in 3D-IC designs, resulting in reduced wirelength, footprint, faster speed, improved bandwidth, and lesser routing congestion. However, the usage of TSVs itself gives rise to many critical design challenges towards the minimization of chip delay and power consumption. Therefore, realization of the benefits of 3D ICs necessitates an early and realistic prediction of circuit performance during the early layout design stage. The goal of this thesis is to meet the design challenges of 3D ICs by providing new capabilities to the existing floorplanning framework [87]. The additional capabilities included in the existing floorplanning tool is the co-placement of TSV islands with circuit blocks and performing non-deterministic assignment of signals to TSVs. We also replace the wirelength and number of TSVs in the floorplanning cost function with the total delay in the nets. The delay-aware cost function accounts for RC delay impact of TSVs on the delay of individual signal connection, and obviates the efforts required to balance the weight contributions of wirelength and TSVs in the wirelength-aware floorplanning. Our floorplanning tool results in 5% shorter wirelength and 21% lesser TSVs compared to recent approaches. The delay in the cost function improves total delay in the interconnects by 10%-12% compared to wirelength-aware cost function. I would like to express my sincere gratitude to my advisor Prof. Malgorzata Chrzanowska-Jeske for the continuous support of my Ph.D. study and related research, for her patience, motivation, and immense knowledge. Her guidance helped me immensely in all the time of research and writing of this thesis. She was always available for my questions and gave generously for her time and vast knowledge. Besides my advisor, I would like to thank the rest of my thesis committee: Dr. W.