Tu1039: REAL-LIFE PATIENT EDUCATIONAL RECORDING BEFORE ESOPHAGEAL MANOMETRY SIGNIFICANTLY IMPROVES KNOWLEDGE AND PATIENT SATISFACTION AND REDUCES ANXIETY AND PROCEDURAL ABORTION RATE

Yip, Coka K.; Kim, Linda; Rezaie, Ali; Sotelo, Cinthya; Xu, Wenrui; Chang, Binxia; Lees-Kim, Vicky; Layaoen, Lorna; Cabili-Lopez, Lourdes; Winokur, Elizabeth J.

doi:10.1016/s0016-5085(22)62028-6

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“…Intolerance of HRM was more commonly seen in children and seniors compared with adults aged 18–79 years and was due to minor symptoms of discomfort without any serious complications. As the use of HRM in diagnosing esophageal motility disorders grows, there is a need to address intolerability risks with solutions such as implementing educational videos of a real subject undergoing manometry ( 23 ) or using medications such as oral viscous lidocaine. Future development of pediatric-sized HRM catheters can also be suggested, given nearly 40% of those who failed manometry required endoscopic interventions.…”

Section: Discussionmentioning

confidence: 99%

Safety and Tolerability of High-Resolution Esophageal Manometry in Children and Adults

Huang²,

Takakura

et al. 2023

Clin Transl Gastroenterol

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INTRODUCTION: While high-resolution manometry (HRM) is widely accepted as a safe procedure, no study has assessed the safety profile of HRM in clinical practice. This study aimed to determine the safety and tolerability of HRM and to investigate potential determinants of intolerability. METHODS: We obtained HRM procedure reports, demographics, and clinical data (2005–2022) at a tertiary center using electronic chart review. Our primary outcome was HRM tolerability. Multivariable regression was performed to identify associations between the outcome and covariates including age, sex, race, and comorbidities. RESULTS: A total of 5,107 patients (60.3% female) were included. Of them, 5,050 patients (98.9%) tolerated HRM well and 57 patients (1.1%) did not. Age had a statistically significant effect on tolerance: those younger than 18 years had more than a 5-fold increase in not tolerating HRM compared with those aged 18–79 years (5.77% vs 0.99%; odds ratio [OR] = 5.44, 95% confidence interval [CI] 1.60–18.45; P = 0.007), and those aged 80 years or older were also more likely to terminate HRM (2.43% vs 0.99%; OR = 2.56, 95% CI 1.13–5.76; P = 0.024). While prior foregut surgery had a significant effect on tolerance (OR = 8.06, 95% CI 2.29–28.39; P = 0.001), other factors of race, sex, body mass index, and psychological or cognitive disorders had no significant impact. No serious complications were identified. DISCUSSION: HRM is safe and well-tolerated with approximately 1 in every 100 patients being unable to tolerate HRM. Intolerance was more commonly seen in children and seniors due to minor symptoms of discomfort without serious complications. These data points are crucial to counsel patients in whom HRM is being considered.

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Section: Discussionmentioning

confidence: 99%