Tu1570 IS IR GASTROSTOMY PLACEMENT SAFER THAN PEG? A RETROSPECTIVE REVIEW OF 461 PATIENTS FROM 2014-2019

Abstract

pain (83%), diarrhea (67%), hematochezia (42%), iron deficiency anemia (8%), and/ or elevated C-reactive protein level (CRP; 8%). Of those with imaging (nZ11), one showed terminal ileum dilatation whereas the rest were normal. All patients underwent upper endoscopy (EGD) with duodenal erythema (25%), erosions (17%), nodularity (17%), friability (8%), or congestion (8%). Of those who underwent ileoscopy or colonoscopy (nZ9), small bowel/terminal ileum findings included erosions (22%), ulcers (11%), and dilatation (11%). All VCEs were abnormal with small bowel findings of erosions (83%), inflammatory changes (erythema, edema, and granularity; 83%), ulcerations (75%), and blood/hematin (50%). Both patients without abdominal pain had disease on VCE, as did all three patients without anemia and all three patients without elevated CRP. Of those with EGD, VCE, and colonoscopy evaluation (nZ11), disease was seen in all three modalities in 72.7%, VCE and colonoscopy only in 18.2%, or EGD and VCE only in 9.1%. Conclusions: CGD patients with GI symptoms often have active small bowel disease. In such patients, small bowel disease should be investigated, and therapy should seek to address any small bowel involvement. These interim results support continued exploration and characterization of small bowel disease in CGD and its optimal diagnostic modality.