Tu1785 Trends in Acute Cholecystitis With and Without Choledocholithiasis

Grinberg, Roman; Afthinos, John; Gibbs, Karen E.

doi:10.1016/s0016-5085(15)34033-6

Cited by 1 publication

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“…A total of 715 studies were identified by the initial search. After applying the inclusion and exclusion criteria, 693 studies were excluded, leaving 22 studies to be included in our analysis (Fig. ).…”

Section: Resultsmentioning

confidence: 99%

“…included 2588 patients diagnosed with AC, of which only 248 (9.6%) had biliary imaging and was not used for assessing cumulative CBDS calculations. A funnel plot was performed and two outlier studies were excluded (Fig. S1).…”

Section: Resultsmentioning

confidence: 99%

“…Two studies employed a combination of histology and clinical diagnosis . The method of AC diagnosis was not reported in six studies . Patients from studies of histologically confirmed AC had similar incidence of CBDS compared with those diagnosed clinically (15.4% versus 13.4%; P = 0.159).…”

Section: Resultsmentioning

confidence: 99%

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Incidence and predictors of common bile duct stones in patients with acute cholecystitis: a systematic literature review and meta‐analysis

Chen

Jorissen

Walcott

et al. 2019

ANZ Journal of Surgery

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Background Acute cholecystitis (AC) is a surgical condition that is usually managed by emergency surgery. The presence of common bile duct stones (CBDS) in this setting mandates definitive treatment to avoid complications such as cholangitis. The incidence of CBDS in the setting of AC is poorly defined. Methods A systematic English literature search was conducted in PubMed, MEDLINE and Embase to determine the incidence of CBDS in patients presenting with AC. Outlier studies identified by funnel plot analysis were excluded and the incidence of CBDS was identified. The mean CBD diameter and liver function test values of patients with AC and CBDS were calculated. Results Data were extracted from 19 studies representing a total 4057 patients with AC. Routine biliary imaging was not performed in all studies. The pooled incidence of CBDS was 13.7% (95% confidence interval 11.8–15.9). The incidence of unsuspected retained CBDS was 1.1%. Histologically confirmed cases of AC had a similar rate of CBDS compared to those diagnosed clinically. The mean CBD diameter of patients with AC and CBDS was 7.2 mm compared to 5.8 mm without. Liver function test values in the presence of CBDS were more likely to be deranged, with gamma‐glutamyltransferase the most sensitive and specific marker for CBDS in the setting of AC. Conclusion CBDS is present in a significant proportion of patients presenting with AC. Routine biliary imaging is advised in all patients presenting with AC where possible.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%