TuBaFrost 6: Virtual microscopy in virtual tumour banking

Teodorović, Ivana; Isabelle, Maripier; Carbone, Antonino; Passioukov, A.; Lejeune, S.; Jaminé, D.; Therasse, Patrick; Gloghini, Annunziata; Dinjens, Winand N.M.; Lam, King H.; Oomen, M.H.A.; Spatz, Alan; Ratcliffe, Chris; Knox, Kirstine A.; Mager, R.; Kerr, David; Damme, B Van; Vijver, Marc J. van de; Boven, Hester van; Morente, Manuel; Alonso, Soledad; Kerjaschki, Dontscho; Pammer, Johannes; Löpez‐Guerrero, José Antonio; Bosch, Antonio Llombart; Veen, Evert-Ben van; Oosterhuis, J. Wolter; Riegman, Peter

doi:10.1016/j.ejca.2006.04.033

Cited by 29 publications

(16 citation statements)

References 12 publications

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“…Mirax TMA Module software (http://www.webmicroscope.net/breastatlas), an excellent tool for both graduate and postgraduate teaching [9]. Its advantages can also be exploited for virtual tumor banking offering a digital slide catalogue and database of large repositories of tumor samples stored at distantly situated laboratories of consortium members [12].…”

Section: Education Teleconsultation and Quality Assurancementioning

confidence: 99%

The Potential of Digital Microscopy in Breast Pathology

Krenács

Zsakovics

Diczhazi

et al. 2008

Pathol. Oncol. Res.

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The rapidly evolving field of digital microscopy supports the efficient exploitation of inherent information from stained glass slides to offer widespread utilization in breast histopathology. Digital image signals can be accurately measured, integrated into databases and shared through computer networks. Therefore, digital microscopy can boost telepathology-consultation, gradual- and postgradual teaching, proficiency testing, intra- and interlaboratory validation of biomarker screening interpretation, and automated image analysis of biomarker expression for both diagnostics and research applications. This is a brief highlight of the potential of digital microscopy in breast pathology applications.

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Section: Education Teleconsultation and Quality Assurancementioning

confidence: 99%

The Potential of Digital Microscopy in Breast Pathology

Krenács

Zsakovics

Diczhazi

et al. 2008

Pathol. Oncol. Res.

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“…For more than decade, digital slide scanners have been available that produce digital slide images (DSIs), also called whole slide images [3,4], which improve the limitations of live imaging-based telepathology [5,6].…”

Section: Introductionmentioning

confidence: 99%

Digital slide images for primary diagnostics in breast pathology: a feasibility study

Al-Janabi¹,

Huisman²,

Willems³

et al. 2012

Human Pathology

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“…In case of multicenter studies it should in addition have an option to export these data only under sample identity or even completely anonymized to other facilities that need the data for analysis. These data can vary depending on the needs of that particular study however and can even be completed with radiology scans and pathology images of macros and histology supported by virtual microscopy [9] . Last but not least, for regional collections of samples an input of external data is required consisting of a flexible web-based system on which forms with programmable questions and preset choices for standardized data input will allow easy data input for regional volunteers.…”

Section: The Role Of Academic Hospitalsmentioning

confidence: 99%

“…To overcome deficiencies at the national level, the academic centers can be organized in larger international networks of virtual tissue banks like for instance TuBaFrost. This network was created in a European framework 5 project for frozen tumor samples [9][10][11][12][13][14] (www.tubafrost.org). It is still active after funding, because it is fully integrated in the OECI (Organisation of European Cancer Institutes).…”

Section: Networkmentioning

confidence: 99%

Biobanking for Interdisciplinary Clinical Research

2007

Self Cite

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Biobanking nowadays is mostly strongly determined by the specific aims of a research group in charge of the biobank, determining their own standards for the collection and annotation of samples. Often a long period is needed to build up the sample and data collections, especially when long-term follow-up data is required. Such collections need a long-term dedication and proper funding. Neglecting either sample number or annotation can result in insignificant or poor results. However, outcome of translational research does not only depend on the sample quality. In many cases it can also be improved to start the experimental design within a multidisciplinary team composed of clinicians including pathologists, molecular biologists, statisticians, bioinformaticians and tissue resource managers. Such a team, capable of careful evaluation of the numbers needed and which or what part of the samples are to be included, could help in obtaining far better results. Many lines of clinical research could benefit more efficiently from the wealth of information stored in well-preserved disease-oriented tissue sample collections with the proper annotations, when the infrastructure around biobanks and new collection build-up is well organized, standardized and streamlined. Future medical research will refine its scientific questions, demanding even further refinement of corresponding clinical information. In addition, larger sample collections are needed to study for instance multifactorial diseases. Today, the samples are collected for tomorrow, therefore, improvement is needed now in standardization, automated enrichment of annotations from hospital information systems and disease registries, insight in overlapping collections of different forms of tissue banking and cooperation in national and international networks.

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TuBaFrost 6: Virtual microscopy in virtual tumour banking

Cited by 29 publications

References 12 publications

The Potential of Digital Microscopy in Breast Pathology

The Potential of Digital Microscopy in Breast Pathology

Digital slide images for primary diagnostics in breast pathology: a feasibility study

Biobanking for Interdisciplinary Clinical Research

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