Tubal Anastomosis in the Rat Using the Tissue Adhesive Cyanoacrylate (Histoacryl&amp;reg;)

Haj, Naif; Haj, Mahmoud; Shasha, Shaul M.; Oettinger, Moshe

doi:10.1159/000292446

Cited by 8 publications

(6 citation statements)

References 4 publications

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“…Haj N et al, retrospectively evaluated major reasons for the request for reversal which were a loss of children 50%, remarriage 27%, 10%. 9 Holst et al, studied comparison between microsurgical and micro laser techniques and concluded that the carbon dioxide laser's advantages (precision, homeostasis and the ability to preserve more normal reproductive tissue), although technically beneficial in performing microsurgical tubal reanastomosis, may not prove to be superior to conventional microsurgical technique as pregnancy rates are compared. Additional long-term studies are needed as more experience is gained to further delineate the role of the carbon dioxide laser for microsurgical tubal reanastomosis.…”

Section: Discussionmentioning

confidence: 99%

Tubal recanalisation-microsurgical tubal reversal anastomosis

Rajendran

2018

Int Surg J

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Background: Nowadays, in India, to control population, we are strictly following permanent methods of sterilization after one or two children. Because of some unfortunate things like RTA or some natural calamities, some parents have lost one or both the children in that situation. To study the outcome of the procedure patency of the tube, complications, pregnancy if happens during the study period.Methods: Totally 65 female patients were included in the study. Authors have the patients for past 18 years including post tubectomy patients with is variable age and duration after sterilization and all methods of sterilization except fimbriectomy. For all cases, we have done all basic investigation, USG, and HSG.Results: Totally 65 patients are followed regularly from 2008. The success rate (pregnancy rate) is >90%. In these patients, pregnancy outcome was in form of intrauterine pregnancy (90%) ectopic pregnancy (2%), term viable pregnancy (3%) and spontaneous abortion (less than 1%).Conclusions: In the past, in most of the studies, the success rate (pregnancy rate) is more in the age group of <30 years. But in present study even in >30 years age and any long duration of the post-sterilization period, the success rate is more, because the two-layer technique 8-0 prolene under loupe magnification is the leading factor for the success rate (pregnancy rate).

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Section: Discussionmentioning

confidence: 99%

Tubal recanalisation-microsurgical tubal reversal anastomosis

Rajendran

2018

Int Surg J

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“…it was seen that histologically that there were less foreign body granulomas. [ 5 ] Takenaka et al . clearly showed that cyanoacrylate anastomosis prevents anastomotic neointimal hyperplasia.…”

Section: Discussionmentioning

confidence: 99%

“…The use of cyanoacrylate for anastomosis of vessels, the urogenital tract, and bowel have been reported in different experimental models ranging from rat to rabbits, and dogs and monkeys, with varying outcomes. [ 5 – 8 ]…”

Section: Introductionmentioning

confidence: 99%

The use of cyanoacrylate in surgical anastomosis: An alternative to microsurgery

Bot

Ogunranti

et al. 2010

J Surg Tech Case Report

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To present anastomosis with cyanoacrylate as a cheap, simple, fast, and available technique for anastomosis in urological, vascular, gynecological, and general surgical procedures. This method may in the future be a good alternative to microsurgery, particularly in centers where facilities are unavailable and the financial implication is unbearable for the patient. Cyanoacrylate is an adhesive or glue that is available in different chemical forms ranging from ethylcyanoacrylate (superglue) to Isobutylcyanoacrylate and octylcyanoacrylate (dermerbond), which is in clinical use. Anastomosis with cyanoacrylate requires the application of stay sutures, a luminal stent and the subsequent application of the adhesive. The adhesives with lower molecular weights produce a rigid and patent region of anastomosis, while the higher molecular compounds produce a consistency close to the normal tissue. This technique presents a surgical method that is socially, culturally, and ethically acceptable, which is affordable to a larger majority of patients in our subregion. Cyanoacrylate anastomosis may in the future present a fast, convenient, simple, and affordable option in the treatment of patients requiring anastomosis. In our subregion where the socio-cultural, psychological, and economic burden of failed anastomosis is high, associated with the low per capital income, this may be a novel option for the management of urogynecological, vascular, neurosurgical, and general surgical procedures requiring either microscopic or macroscopic anastomosis.

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“…To overcome these shortcomings, various techniques with different surgical materials have been studied. Fibrin glue [9 -12] and cyanoacrylate [13,14] were found to be as effective as standard microsurgical anastomosis with suture materials. Autologous fibrin was associated with superior results compared to heterologous fibrin and conventional sutures [15,16].…”

Section: Discussionmentioning

confidence: 99%

Histological Evaluation of a New Concept Eliminating the Need for Suture or Glue During Fallopian Tube Anastomosis in the Sheep Model

Kaya¹,

Özkaya²,

Sezi̇k³

et al. 2005

Geburtsh Frauenheilk

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Objective: To evaluate the pathological outcomes of a newly introduced technique for tubal anastomosis in an animal model. Materials and Methods: The uterine tubes of 12 sheep were transected bilaterally. A polyvinyl chloride catheter was passed through the fimbrial end. The resected ends were approximated, and the catheter was fixed in place using titanium clips. No suture material or glue was used. The time required for the procedure, patency of the tubes, fibrosis, giant cell reaction, inflammation, and luminal changes were evaluated 30 days after surgery. Results: Epithelial continuity was present in 21 (87.5 %) of the resected tubes. Acute inflammatory changes and herniation leading to fistulization were observed in 2 (8.3 %) and 1 (4.2 %) of the specimens, respectively. There was no fibrosis or giant cell reaction. Conclusion: Passage of an inert catheter left in situ for tubal anastomosis is associated with a high rate of reepithelization in an animal model. Our technique might have potential use in uterine tube reconstruction. Zusammenfassung Fragestellung: Histologische Evaluation einer neuen Technik zur Tubenanastomose im Tiermodell. Methode: Eileiter von 12 Schafen wurden bilateral durchtrennt. Ausgehend vom Fimbrientrichter wurde ein Polyvinylkatheter in die Tube eingefügt. Die freien Enden wurden zusammengefügt und der Katheter mithilfe von Titanklemmen ohne Verwendung von Faden oder Klebematerial fixiert. Die Operationsdauer, die Tubendurchgängigkeit, die Bildung von Fibrosen, Granulomen, Entzündungen und Lumenänderungen wurden 30 Tage nach Eingriff evaluiert. Ergebnisse:In 21 (87,5 %) der resezierten Tuben konnte durchgängiges Epithel gefunden werden. Akute entzündliche Veränderungen und Fistelbildung wurden in 2 (8,3 %) beziehungsweise in 1 (4,2 %) der Fälle beobachtet. Es gab keine Fibrosen oder Granulome. Schlussfolgerung: Die Verwendung eines inerten Katheters für die tubare Anastomose im Tiermodell führt in situ zu einer hohen Rate an Reepithelisierung. Die vorgestellte Technik verspricht eine mögliche Anwendung in der Tubenrekonstruktion. Schlüsselwörter Eileiterrekonstruktion · Tubenanastomose · KatheterOriginalarbeit 682 Institutsangaben

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Tubal Anastomosis in the Rat Using the Tissue Adhesive Cyanoacrylate (Histoacryl®)

Cited by 8 publications

References 4 publications

Tubal recanalisation-microsurgical tubal reversal anastomosis

Tubal recanalisation-microsurgical tubal reversal anastomosis

The use of cyanoacrylate in surgical anastomosis: An alternative to microsurgery

Histological Evaluation of a New Concept Eliminating the Need for Suture or Glue During Fallopian Tube Anastomosis in the Sheep Model

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