Tube Polypropylene: A Neglected Critical Parameter for Protein Adsorption During Biospecimen Storage

Kofanova, Olga; Mommaerts, Kathleen; Betsou, Fay

doi:10.1089/bio.2014.0082

Cited by 18 publications

(13 citation statements)

References 16 publications

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“…However, this could be alleviated by preventing bacterial growth with 0.1% sodium azidewhich did not alter starting concentrations even after 5 days at RT [133]. In addition, tube sterilization methods can significantly increase their adsorbance properties (e.g., irradiation significantly increased the adsorbance properties of homopolymer tubes [121]). Further analysis into these potential variables may be required.…”

Section: Additional Variablesmentioning

confidence: 99%

The impact of preanalytical variables on measuring cerebrospinal fluid biomarkers for Alzheimer's disease diagnosis: A review

Hansson

Mikulskis

Fagan

et al. 2018

Alzheimer's & Dementia

102

110

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Section: Additional Variablesmentioning

confidence: 99%

The impact of preanalytical variables on measuring cerebrospinal fluid biomarkers for Alzheimer's disease diagnosis: A review

Hansson

Mikulskis

Fagan

et al. 2018

Alzheimer's & Dementia

102

110

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“…Even temporary storage in 0 or 4 °C exposes samples to evaporation [ 65 ]. Another often neglected issue is storage container selection, when choosing the wrong polypropylene tube type may decrease the yield of protein extraction [ 66 ]. The other essential step of pre-analytical samples’ management is to implement a replicable, precise and errorless aliquoting workflow.…”

Section: Basic Components Of Biobankmentioning

confidence: 99%

Aspects of Modern Biobank Activity – Comprehensive Review

Paskal

Dębski

et al. 2018

Pathol. Oncol. Res.

102

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Biobanks play an increasing role in contemporary research projects. These units meet all requirements to regard them as a one of the most innovative and up-to-date in the field of biomedical research. They enable conducting wide-scale research by the professional collection of biological specimens and correlated clinical data. Pathology units may be perceived roots of biobanking. The review aims at describing the concept of biobanks, their model of function and scientific potential. It comprises the division of biobanks, sample preservation methods and IT solutions as well as guidelines and recommendations for management of a vast number of biological samples and clinical data. Therefore, appropriate standard operating procedures and protocols are outlined. Constant individualization of diagnostic process and treatment procedures creates the niche for translational units. Thus, the role of biobanks in personalized medicine was also specified. The exceptionality of biobanks poses some new ethical-legal issues which have various solutions, in each legal system, amongst the world. Finally, distribution and activity of European biobanks are mentioned.

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“…Очень важным моментом является выбор контейнеров для размещения аликвот. Размещение проб в контейнерах, не предназначенных для заморозки (типа эппендорф), недопустимо и нивелирует ценность хранящихся образцов [16].…”

Section: общие принципы инфраструктуры биобанкаunclassified

Biobanks in oncology: global experience and Russian reality

et al. 2020

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One of the integral components of modern large-scale research projects in the field of medicine are biobanks. The main objective of this infrastructure is the professional collection of biological samples that can be studied with respect to a wide range of molecular biological parameters and will not lose their information value over a long storage period. These samples are made informative not only by correctly conducted preanalytical preparation at the stage of taking samples and placing them in storage, but also by detailed information support (the so-called annotated samples). The sample annotation is the fully collected personal, clinical and laboratory data about a patient. An important point of the biobank infrastructure is compliance with regulatory legal acts and ethical standards, including the procedure for signing an informed consent by a patient about voluntary donation of biological samples and the use of personal data. All this ensures the implementation of the main objective of creating biobanks the wide and uninterrupted availability of collections of biological material for researchers and developers and compliance with specific scientific tasks. This review is devoted to biobanking issues, as well as to the description and analysis of the currently existing oncological biobank infrastructure, both globally and within the Russian Federation.

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Tube Polypropylene: A Neglected Critical Parameter for Protein Adsorption During Biospecimen Storage

Abstract: This biospecimen research case study illustrates the importance of a neglected pre-analytical factor, the polypropylene type of storage tubes. We measured amyloid β1-42 peptide and showed that a non-irradiated, homopolymer type of polypropylene has the lowest adsorption properties.

Cited by 18 publications

References 16 publications

The impact of preanalytical variables on measuring cerebrospinal fluid biomarkers for Alzheimer's disease diagnosis: A review

The impact of preanalytical variables on measuring cerebrospinal fluid biomarkers for Alzheimer's disease diagnosis: A review

Aspects of Modern Biobank Activity – Comprehensive Review

Biobanks in oncology: global experience and Russian reality

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