Tuberculome cérébral chez une enfant de 10 ans diagnostiqué par biopsie d’une adénopathie abdominale

Vernaz, A; Enaud, L.; Blanc, S.; Stoven, C.; Tasset, Chantal; Losi, S.; Andriolo, E.; Piyaraly, S.; Flodrops, H.

doi:10.1016/j.arcped.2012.05.014

Cited by 2 publications

(7 citation statements)

References 12 publications

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“…Cerebral tuberculomas can occur anywhere in the brain. Classically, they are supratentorial in adults and infratentorial in children [ 8 , 12 ]. Intracranial tuberculoma is most often unique (90%) [ 1 , 8 ].…”

Section: Discussionmentioning

confidence: 99%

Cerebral tuberculoma and convulsion in infants: A case report

Cherraqi¹,

Haddad²,

Abide³

et al. 2023

Radiology Case Reports

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Section: Discussionmentioning

confidence: 99%

Cerebral tuberculoma and convulsion in infants: A case report

Cherraqi¹,

Haddad²,

Abide³

et al. 2023

Radiology Case Reports

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“…This case presented meningeal tuberculosis and abdominal IP-associated TB, this combination is rare but some cases have been published [13,16,17,[19][20][21]. Vernaz et al [20] noted a case with frontal lesions suggestive of a tumor process and abdominal mass, with thoracoabdominal and mesenteric adenopathies.…”

Section: Discussionmentioning

confidence: 99%

“…Vernaz et al [20] noted a case with frontal lesions suggestive of a tumor process and abdominal mass, with thoracoabdominal and mesenteric adenopathies. Hablani et al [17] reported the imaging features of four cases of abdominal pseudotumor TB in order to demonstrate diagnostic difficulties.…”

Section: Discussionmentioning

confidence: 99%

“…Abdominal mass and retroperitoneal TB which have increased in recent years only contribute to 1% of clinical manifestations of disease [13,[16][17][18][19][20].…”

Section: Discussionmentioning

confidence: 99%

“…The differential diagnosis of mesenteric and retroperitoneal mass also included lymphoma, leiomyosarcoma, GIST, desmoid tumor, Wegener's granulomatosis, IP, and TB [13,16,17,[19][20][21].…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Cystic Mesenteric Inflammatory Pseudotumor Associated to Multidrug-Resistant Meningeal Tuberculosis and a Cerebrospinal Fluid Shunt: An Unusual Case

Tena-Suck¹,

Soto-Hernández²,

Gonzalez-Mosqueda³

et al. 2015

J Neurol Res

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Abdominal masses in childhood have a very large spectrum of benign and malignant causes. Inflammatory pseudotumor (IP) arising from intra-abdominal sites has only rarely been designated previously in children. We report the case of a 21-year-old HIV-negative man, in whom a cystic mesenteric IP appeared after 46 months of diagnosis of tuberculous meningitis (TBM) complicated with brain infarcts, tuberculoma, hydrocephalus and multiple neurosurgical procedures including ventriculoperitoneal (VP) cerebrospinal fluid (CSF) shunt placement, shunt exchanges and endoscopic ventricular septostomies. At diagnosis, primary antituberculous drugs were administered and mycobacterial CSF cultures were persistently negative; nevertheless, follow-up elevated adenosine deaminase levels in CSF suggested multidrug-resistant (MDR) tuberculosis and moxifloxacin and aminoglycoside were added with improvement. Repeated formation of abdominal cystic masses with shunt obstructions, abdominal distention and pain lead us to conclude that the peritoneum was no longer useful for CSF derivation and a ventriculo-atrial shunt was placed. After laparoscopic excision of an abdominal mass, microscopic examination showed a cystic tumor formed by proliferation of fibroblasts, myofibroblasts and inflammatory cells. Focally a granuloma with multinucleated giant cells (Langerhans cells) was observed and Ziehl-Neelsen staining showed acid-fast bacilli. Diagnosis of IP associated to MDR tuberculosis was made. This complication is probably under-recognized since histopathological study of abdominal masses related with CSF VP shunts is not performed systematically. Our case illustrates the importance of microscopic tissue examination to detect MDR and extensively drug-resistant (XDR) tuberculosis and the difficult treatment of these cases.

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Tuberculome cérébral chez une enfant de 10 ans diagnostiqué par biopsie d’une adénopathie abdominale

Cited by 2 publications

References 12 publications

Cerebral tuberculoma and convulsion in infants: A case report

Cerebral tuberculoma and convulsion in infants: A case report

Cystic Mesenteric Inflammatory Pseudotumor Associated to Multidrug-Resistant Meningeal Tuberculosis and a Cerebrospinal Fluid Shunt: An Unusual Case

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