Tuberculose néonatale: Difficulté du diagnostic précoce

Pillet, P.; Grill, J.; Rakotonirina, Gervais; Holvoet-Vermaut, L.; Aurégan, G; Guyon, Philippe

doi:10.1016/s0929-693x(99)80294-2

Cited by 14 publications

(1 citation statement)

References 7 publications

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“…The transmission may occur in utero (congenital transmission) or during delivery (perinatal transmission). It is a rare disease with a high mortality rate of approximately 50% [1,2]; birth is usually premature [1,3], although term deliveries have been described [4,5]. Perinatal transmission can be by aspiration, ingestion of infected amniotic fluid, hematogenous spread, endometritis [6], or rarely through ingestion of breast milk.…”

Section: Introductionmentioning

confidence: 99%

Perinatally Acquired Tuberculosis in a Neonate

et al. 2004

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Objectives: To report a case of perinatal tuberculosis that appeared on the 21th day of life of an infant born to a mother with latent tuberculosis. Clinical Presentation and Intervention: A preterm male infant was born by spontaneous vertex delivery at 33 weeks gestational age to a 33-year-old primiparous Philippine woman. The infant was well until the 21st day of life when he developed recurrent episodes of cyanosis and bradycardia. A chest radiograph showed infiltrates which were thought to be bacterial in origin. Blood, urine, and cerebrospinal fluid cultures were normal. Tracheal aspirate revealed acid-fast bacilli by Ziehl-Neelsen stain, later confirmed to be Mycobacterium tuberculosis by culture in Lowenstein-Jensen medium. The mother was later diagnosed as a case of tuberculosis with symptoms, signs and radiologic manifestation of hilar lymphadenopathy with mild pleural effusion and positive tuberculin skin test. Both infant and mother were treated with intravenous isoniazid, intravenous rifampicin, oral pyrazinamide, and intravenous pyridoxine. Both recovered. Conclusion: A preterm male infant perinatally acquired tuberculosis, most likely by inhalation of the bacteria during delivery. Both infant and mother responded well to antituberculous treatment.

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Section: Introductionmentioning

confidence: 99%

Perinatally Acquired Tuberculosis in a Neonate

et al. 2004

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Analysis of 170 cases of congenital TB reported in the literature between 1946 and 2009

Peng

Yang

Liu

2011

Pediatric Pulmonology

103

122

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Perinatal Tuberculosis

et al. 2001

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Perinatal tuberculosis is insufficiently understood. Its early diagnosis is essential but often difficult as the initial manifestations may be delayed. Improved screening of women at risk and sensitivity of the medical community are necessary. A coherent system of cooperation between the hospital and community services and between pediatricians and adult physicians is indispensable to find the index adult case to break the chain of contagion as well as to offer prophylactic therapy to the children at risk. We hereby report a baby with perinatal tuberculosis who was not offered any prophylactic therapy inspite of the mother being diagnosed to have pulmonary tuberculosis.

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Tuberculose néonatale: Difficulté du diagnostic précoce

Cited by 14 publications

References 7 publications

Perinatally Acquired Tuberculosis in a Neonate

Perinatally Acquired Tuberculosis in a Neonate

Analysis of 170 cases of congenital TB reported in the literature between 1946 and 2009

Perinatal Tuberculosis

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