Tuberculosis (<i>Mycobacterium tuberculosis</i>) in a pregnant baboon (<i>Papio cynocephalus</i>)

Martino, Maurizio de; Hubbard, Gene B.; Schlabritz‐Loutsevitch, Natalia

doi:10.1111/j.1600-0684.2006.00166.x

Cited by 13 publications

(10 citation statements)

References 19 publications

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“…Mortality arising from endocrine system lesions (n = 53) was seen most often in aged (36, 67.9%) baboons, with an approximately 8:1 female to male ratio. Animals with endocrine system-related mortality were much more likely to have been euthanized (44,83.0%) than to have died. Within the endocrine system, the most common causes of mortality were amyloidosis of the islets of Langerhans (38,71.7%) and neoplasia (13,24.5%).…”

Section: Endocrine Systemmentioning

confidence: 99%

“…The systems affected were the digestive (105, 44.3%), urogenital (101, 42,6%), respiratory (26,11.0%), and cardiovascular (5, 2.1%). The most frequent lesions associated with mortality arising from physical etiology were dilatation (44,18.6%), dystocia (38,16.0%), stillborn (32,13.5%), intussusception (28,11.8%), atelectasis (26,11.0%), prolapse (22, 9.3%), and placenta abruptio (10, 4.2%).…”

Section: Physicalmentioning

confidence: 99%

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Mortality in captive baboons (Papio spp.): a‐23‐year study

Dick

Owston

David

et al. 2014

J of Medical Primatology

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Background We report the causes of mortality for 4,350 captive baboons that died or were euthanized due to natural causes during a 23 year period at the Southwest National Primate Research Center. Methods Necropsy records were retrieved and reviewed to determine a primary cause of death or indication for euthanasia. Data was evaluated for morphological diagnosis, organ system and etiology. Results The 20 most common morphologic diagnoses accounted for 76% of the cases, including: stillborn (10.8%); colitis (8.6%); hemorrhage (8.4%); ulcer (5.2%); seizures (4.7%); pneumonia (4.2%); inanition (4.1%); dermatitis (3.8%); spondylosis (3.3%); and amyloidosis (3.0%). The digestive system was most frequently involved (21.3%), followed by the urogenital (20.3%), cardiovascular (12.2%), and multisystem disease (10.3%). An etiology was not identified in approximately one third of cases. The most common etiologies were trauma (14.8%), degenerative (9.5%), viral (8.7%), and neoplastic/proliferative (7.0%). Conclusion This information should be useful for individuals working with baboons.

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Section: Endocrine Systemmentioning

confidence: 99%

Section: Physicalmentioning

confidence: 99%

Mortality in captive baboons (Papio spp.): a‐23‐year study

Dick

Owston

David

et al. 2014

J of Medical Primatology

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“… TST= Tuberculin skin test; AFB= Acid fast bacilli; PCR=Polymerase chain reaction; RFLP=Restriction fragment link polymorphism Sources a (Kennard et al, 1939); b (CDC, 1933); c (Tarara et al, 1985); d (Stockinger DE et al, 2011); e (Garcia et al, 2004); f (West et al, 1981); g (Habel, 1947); h (Martin, 1968); i (Fairbrother, 1932); j (Une Y and Mori, 2007); k (Fox, 1923); l (van Bogaert and Innes, 1962); m (Machotka et al, 1975); n (Zumpe et al, 1980); o (Panarella and Bimes, 2010); p (Rocha et al, 2011); q (Michel et al, 2009); r (Singh et al, 2009); s (Alfonso et al, 2004); t (Amado et al, 2006); u (Martino M et al, 2007); v (Michel et al, 2003) …”

Section: Figurementioning

confidence: 99%

From the Mouths of Monkeys: Detection of Mycobacterium tuberculosis Complex DNA From Buccal Swabs of Synanthropic Macaques

Wilbur

Engel

Rompis

et al. 2012

American J Primatol

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Although the Mycobacterium tuberculosis complex (MTBC) infects a third of all humans, little is known regarding the prevalence of mycobacterial infection in nonhuman primates (NHP). For more than a century, tuberculosis has been regarded as a serious infectious threat to NHP species. Advances in the detection of MTBC open new possibilities for investigating the effects of this poorly understood pathogen in diverse populations of NHP. Here we report results of a cross-sectional study using well-described molecular methods to detect a nucleic acid sequence (IS6110) unique to the MTBC. Sample collection was focused on the oral cavity, the presumed route of transmission of MTBC. Buccal swabs were collected from 263 macaques representing 11 species in four Asian countries and Gibraltar. Contexts of contact with humans included free ranging, pets, performing monkeys, zoos, and monkey temples. Following DNA isolation from buccal swabs, the PCR amplified IS6110 from 84 (31.9%) of the macaques. In general, prevalence of MTBC DNA was higher among NHP in countries where the World Health Organization reports higher prevalence of humans infected with MTBC. This is the first demonstration of MTBC DNA in the mouths of macaques. Further research is needed to establish the significance of this finding at both the individual and population levels. PCR of buccal samples holds promise as a method to elucidate the mycobacterial landscape among NHP, particularly macaques that thrive in areas of high human MTBC prevalence.

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“…Prosimians are also susceptible. The disease is generally associated with infection by the organisms Mycobacterium tuberculosis and M. bovis (Hessler and Moreland, 1968;Renner and Bartholomew, 1974;Thoen et al, 1977;Kaufmann and Anderson, 1978;McLaughlin, 1978;Tarara et al, 1985;Ward et al, 1985;Wolf et al, 1988;Keet et al, 1996;Martino et al, 2007;Panarella and Bimes, 2010); however, a number of other Mycobacterium species have occasionally been reported in association with clinical pulmonary disease (King, 1993b;Chege et al, 2008). Nontuberculous mycobacterial infection is also recognized in nonhuman primates, usually associated with agents belonging to the Mycobacterium avium-intracellulare complex, but also reported in association with M. paratuberculosis.…”

Section: Tuberculosismentioning

confidence: 99%