Tuberculosis in Lung Transplant Recipients

Bravo, Carlos; Roldán, Javier de Gracia; Román, Antonio; Degracia, Javier; Majó, Joaquim; Guerra, Javier; Monforte, Vı́ctor; Vidal, Rafael; Morell, Ferrán

doi:10.1097/01.tp.0000147784.53188.dc

Cited by 49 publications

(36 citation statements)

References 25 publications

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“…In renal transplant recipients, M. tuberculosis was reported in less than 1% of patients in Western countries [5][6][7], 0.8% to 1.6% in Spain [ 8 , 9 ], 2.6% to 3.1% in Turkey [ 10 , 11• ], 1.28% to 5.2% in China [ 12• ] and Taiwan [ 13• , 14• ], and in up to 15% in India [ 15 ]. M. tuberculosis infection after lung transplantation occurs in 0.76% to 6.4% of patients [16][17][18][19]. A 1.8% to 3.5% incidence has been described in liver transplant recipients, but the literature is scarce [ 12• , 20• , 21 ].…”

Section: Incidencementioning

confidence: 99%

Incidence and management of mycobacterial infection in solid organ transplant recipients

Fan

Hadjiliadis²

2009

Curr Infect Dis Rep

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Although advances in surgical technique, immunosuppressive regimens, and medical management have led to improved survival and quality of life after solid organ transplantation, infection continues to represent a major cause of morbidity and mortality in transplant recipients. Immunosuppressive therapy after transplantation compromises cell-mediated immunity in particular, leaving the patient at risk for opportunistic as well as routine community-acquired infections. Mycobacterial infection is a rare but important complication of solid organ transplantation, presenting significant risk to the patient and challenges in terms of treatment. The available literature consists predominantly of case reports and institutional experiences. This article examines both Mycobacterium tuberculosis and nontuberculous mycobacterial infection in the transplant setting.

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Section: Incidencementioning

confidence: 99%

Incidence and management of mycobacterial infection in solid organ transplant recipients

Fan

Hadjiliadis²

2009

Curr Infect Dis Rep

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“…The frequency of TB was 1.32% for LTR and the incidence was 70 times higher in the Spanish Network for Research in Transplant Infections (RESITRA) cohort than in the general population . Other smaller series have reported even higher frequencies (10%) . To reduce this high prevalence, it is essential to determine whether the commonly used risk factors (tuberculin skin test [TST], chest x‐ray, history of TB) are suitable for selecting the at‐risk population in which to initiate prophylaxis .…”

mentioning

confidence: 99%

Risk of tuberculosis after lung transplantation: the value of pretransplant chest computed tomography and the impact of mTOR inhibitors and azathioprine use

Arrabal

Santos

Redel-Montero

et al. 2016

Transplant Infectious Dis

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“…In lung transplant recipients, the development of TB can be due to airborne spread in the community, transmission from the donor (8, 9), or reactivation of quiescent lesions in the native lung. However, only a handful of cases of TB have been reported after lung transplantation to date (9–11), and no paradoxical reactions were noted in these cases.…”

Section: Discussionmentioning

confidence: 99%