Tuberculosis infection in Chinese patients undergoing continuous ambulatory peritoneal dialysis

Lui, Sing Leung; Tang, Sydney C.W.; Li, Fu Keung; Choy, Bo Ying; Chan, Tak Mao; Lo, Wai Kei; Lai, Kar Neng

doi:10.1053/ajkd.2001.28599

Cited by 63 publications

(70 citation statements)

References 18 publications

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“…57 Treatment consists of long-term antituberculous drugs; a suggested regimen is isoniazid, rifampicin, pyrazinamide and ofloxacin for 9-15 months. 58 Catheter removal is usually undertaken, 57,59 although it is not considered necessary for cure. Mortality attributable to tubercular peritonitis is approximately 15%, and much of this may be due to treatment delay.…”

Section: Management Of Peritoneal Dialysis Peritonitismentioning

confidence: 99%

The surgical management of peritoneal dialysis catheters

Brook

White²,

Waller³

et al. 2004

Ann R Coll Surg Engl

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Section: Management Of Peritoneal Dialysis Peritonitismentioning

confidence: 99%

The surgical management of peritoneal dialysis catheters

Brook

White²,

Waller³

et al. 2004

Ann R Coll Surg Engl

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“…A high prevalence of tuberculosis has been reported in dialysis patients, especially in areas where tuberculosis is endemic [2][3][4][5]. Extra-pulmonary tuberculosis is particularly common among dialysis patients and accounts for nearly 50% of cases [2][3][4][5]. Tuberculous (TB) lymphadenitis is a relatively common form of extra-pulmonary tuberculosis [6].…”

Section: Introductionmentioning

confidence: 99%

Tuberculous lymphadenitis in patients undergoing continuous ambulatory peritoneal dialysis

et al. 2007

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The aim of this study was to review the clinical features of tuberculous (TB) lymphadenitis in patients undergoing continuous ambulatory peritoneal dialysis (CAPD). Nine cases of TB lymphadenitis were diagnosed among 910 patients over a period of 10 years. There were five men and four women with a mean age of 51 +/- 15.5 years. The TB lymphadenitis involved the cervical lymph nodes in six patients, supraclavicular lymph nodes in two patients and mediastinal lymph nodes in one patient. Six patients presented with clinically enlarged lymph nodes of whom four also had fever. Three other patients were incidentally found to have enlarged lymph nodes on routine chest X-ray or ultrasound examination of the neck. Diagnosis of TB lymphadenitis was made by demonstrating caseating granulomata with or without positive acid-fast bacilli on excisional lymph node biopsy. All patients were cured with standard anti-tuberculosis drugs for 12 months. No recurrence of the TB lymphadenitis was observed after a mean follow-up of 59 +/- 30 months. We conclude that TB lymphadenitis is not uncommon among patients on CAPD. A high index of suspicion is needed for early diagnosis of this condition. Prompt initiation of anti-tuberculosis treatment is associated with good prognosis.

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“…An extraperitoneal focus was not detected in any tuberculosis patients receiving CAPD. According to this data, it is suggested that CAPD patients with tuberculous peritonitis might have acquired the infection by direct contamination of peritoneal dialysis fluid, rather than by spread from another tuberculosis focus in the body [9]. In contrast to these patients, our case was with concomitant pulmonary and peritoneal tuberculosis.…”

Section: Discussionmentioning

confidence: 60%

Pulmonary and peritoneal tuberculosis in a CAPD patient

et al. 2006

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Patients with chronic renal failure have an increased incidence of tuberculosis due to decreased cellular immunity. More than half of the tuberculosis infection in these patients presented with extrapulmonary involvement. Tuberculous peritonitis is an important problem in patients undergoing continuous ambulatory peritoneal dialysis (CAPD). Simultaneous pulmonary and peritoneal tuberculosis is a very rare condition. We describe a 39-year-old man with culture negative CAPD peritonitis. In spite of conventional antimicrobial therapy the patient had persistent fever, weight loss, and night sweats. Approximately after one month from starting treatment, both sputum specimen and peritoneal fluid were positive for mycobacterium. Quadruple therapy for tuberculosis has been started. The response to treatment was promptly. He is still on treatment for six months and receiving CAPD. Tuberculous peritonitis should always be considered when patients on CAPD develop culture negative peritonitis treated with conventional antibiotics without improvement. In addition, the existence of extraperitoneal tuberculosis, especially pulmonary disease must be investigated.

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Tuberculosis infection in Chinese patients undergoing continuous ambulatory peritoneal dialysis

Cited by 63 publications

References 18 publications

The surgical management of peritoneal dialysis catheters

The surgical management of peritoneal dialysis catheters

Tuberculous lymphadenitis in patients undergoing continuous ambulatory peritoneal dialysis

Pulmonary and peritoneal tuberculosis in a CAPD patient

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