Tuberculosis sequelae assessment and rehabilitation

Muñoz-Torrico, Marcela; Cid-Juárez, Silvia; Galicia-Amor, Susana; Troosters, Thierry; Spanevello, Antonio

doi:10.1183/2312508x.10022317

Cited by 5 publications

(14 citation statements)

References 59 publications

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“…TB sequelae are likely to follow delayed diagnosis, extensive disease, and long and/or repeated treatments [42]. TB sequelae are risk factors for bronchiectasis and COPD (chronic obstructive pulmonary disease), both conditions are more common in smokers and in the presence of in-door or out-door drug pollution [43]. The most common alterations are represented by obstructions with or without restriction.…”

Section: Post-tb Treatment Sequelae and Rehabilitationmentioning

confidence: 99%

“…Airflow obstruction is usually without response to the bronchodilator, and often coupled with bronchiectasis and/or tracheobronchial stenosis, alterations of the lung parenchyma (cavities and pulmonary fibrosis) or of the pleura (empyema, fibrothorax, bronchopleural fistula, and pneumothorax). Restriction can affect gas exchange, as well as other vascular complications including pulmonary or bronchial arteritis, thrombosis, artery dilatation, Rasmussen aneurysm, or 'cor pulmonale' [43]. Both mechanical and gas exchange alterations can limit daily activities, exercise capacity, and impair quality of life (QoL) [43].…”

Section: Post-tb Treatment Sequelae and Rehabilitationmentioning

confidence: 99%

“…Restriction can affect gas exchange, as well as other vascular complications including pulmonary or bronchial arteritis, thrombosis, artery dilatation, Rasmussen aneurysm, or 'cor pulmonale' [43]. Both mechanical and gas exchange alterations can limit daily activities, exercise capacity, and impair quality of life (QoL) [43].…”

Section: Post-tb Treatment Sequelae and Rehabilitationmentioning

confidence: 99%

“…A baseline examination with functional evaluation can be performed safely when the patient is smear and culture negative (on at least two samples two weeks apart) and is undergoing effective treatment; otherwise, infection control measures are necessary [13]. As the patient might need a different approach when resting and when making exercise (e.g., walking), a careful evaluation should be ideally performed both at rest and under exercise conditions [43,44].…”

Section: Post-tb Treatment Functional Evaluationmentioning

confidence: 99%

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Post-Tuberculosis (TB) Treatment: The Role of Surgery and Rehabilitation

et al. 2020

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Even though the majority of tuberculosis (TB) programmes consider their work completed when a patient is ‘successfully’ cured, patients often continue to suffer with post-treatment or surgical sequelae. This review focuses on describing the available evidence with regard to the diagnosis and management of post-treatment and surgical sequelae (pulmonary rehabilitation). We carried out a non-systematic literature review based on a PubMed search using specific key-words, including various combinations of ‘TB’, ‘MDR-TB’, ‘XDR-TB’, ‘surgery’, ‘functional evaluation’, ‘sequelae’ and ‘pulmonary rehabilitation’. References of the most important papers were retrieved to improve the search accuracy. We identified the main areas of interest to describe the topic as follows: 1) ‘Surgery’, described through observational studies and reviews, systematic reviews and meta-analyses, IPD (individual data meta-analyses), and official guidelines (GRADE (Grading of Recommendations Assessment, Development and Evaluation) or not GRADE-based); 2) Post-TB treatment functional evaluation; and 3) Pulmonary rehabilitation interventions. We also highlighted the priority areas for research for the three main areas of interest. The collection of high-quality standardized variables would allow advances in the understanding of the need for, and effectiveness of, pulmonary rehabilitation at both the individual and the programmatic level. The initial evidence supports the importance of the adequate functional evaluation of these patients, which is necessary to identify those who will benefit from pulmonary rehabilitation.

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Section: Post-tb Treatment Sequelae and Rehabilitationmentioning

confidence: 99%

Section: Post-tb Treatment Sequelae and Rehabilitationmentioning

confidence: 99%

Section: Post-tb Treatment Sequelae and Rehabilitationmentioning

confidence: 99%

Section: Post-tb Treatment Functional Evaluationmentioning

confidence: 99%

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Post-Tuberculosis (TB) Treatment: The Role of Surgery and Rehabilitation

et al. 2020

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“…A later chapter includes both treatment and therapeutic drug monitoring, noting that the latter will become increasingly important in personalised treatments regimens [22]. Rehabilitation after TB has become an important topic and receives its own chapter [23]. NTM have been included, as they are frequently diagnosed when TB is considered their increasing importance may merit an entire Monograph in the not-too-distant future [24]!…”

Section: Giovanni Battista Migliorimentioning

confidence: 99%