Tuberculous cerebellar abscess in immunocompetent individuals: Figure 1

Vr, Roopesh Kumar; Sk, Gundamaneni; Biswas, Rakhi; Vs, Madhugiri

doi:10.1136/bcr-2012-006984

Cited by 10 publications

(7 citation statements)

References 3 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The consequences of untreated neurotuberculosis are devastating, and choosing the proper treatment regimen is imperative. [ 7 ] One of the most important components of treatment consists of long-term antituberculosis drug therapy. [ 7 ] Surgical drainage and excision, as in our case, can be used to obtain a microbiological diagnosis and to relieve mass effect caused by large lesions.…”

Section: Discussionmentioning

confidence: 99%

“…[ 7 ] One of the most important components of treatment consists of long-term antituberculosis drug therapy. [ 7 ] Surgical drainage and excision, as in our case, can be used to obtain a microbiological diagnosis and to relieve mass effect caused by large lesions. [ 6 7 ] Most commonly, treatment of tuberculosis lesions involves a pattern of decreasing abscess size on anti-TB drug treatment.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Paradoxical evolution of a cerebellar tuberculosis abscess after surgical drainage and antibiotic therapy

Joshi¹,

Germano²,

Ravindran³

et al. 2014

Surg Neurol Int

View full text Add to dashboard Cite

Background:Involvement of the central nervous system (CNS) by a tuberculosis abscess is a rare form of extra-pulmonary tuberculosis. With proper treatment, the abscess most commonly follows a pattern of continued reduction in size.Case Description:A 71-year-old male with a past medical history of kidney transplant on immunosuppressive therapy, presented to the hospital with a 1-day history of headache. On physical examination, the patient had no focal neurological symptoms. Initial laboratory reports were unremarkable. Contrast enhanced magnetic resonance imaging (MRI) was performed, which showed a ring enhancing mass and perilesional edema in the left cerebellar hemisphere. The patient underwent a left posterior fossa biopsy and drainage. The lesion was encapsulated with a purulent center. Cultures revealed pan-sensitive mycobacterium tuberculosis and the patient was started on rifampicin, isoniazid, pyrazinamide, ethambutol, and B6. The patient was monitored carefully and brain MRIs were obtained at 1, 4, 9, 11, and 14 months. It was noted that the tuberculosis abscess had grown in size from month 4 to month 9 of treatment. Since the patient's neurologic examination and symptoms were stable at that time, the drug regimen was not changed. The 14-month follow up MRI showed that the abscess had nearly resolved.Conclusion:Rarely, the pattern of CNS tuberculosis abscess evolution may include growth, even with proper treatment. This pattern does not necessarily signify treatment failure, as our abscess resolved without change in treatment. Given the possibility of asymptomatic abscess enlargement, close clinical and imaging follow up are crucial in management of these cases.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Paradoxical evolution of a cerebellar tuberculosis abscess after surgical drainage and antibiotic therapy

Joshi¹,

Germano²,

Ravindran³

et al. 2014

Surg Neurol Int

View full text Add to dashboard Cite

show abstract

“…Treatment of tubercular abscess includes antitubercular chemotherapy and surgical excision 2. Most of the published cases of tubercular brain abscess have been dealt with by surgical treatment along with medical management 1 2. We here report a case of intracranial tubercular abscess in a young girl presenting with fever, headache and right hemiparesis who showed significant clinicoradiological improvement with medical management alone.…”

Section: Introductionmentioning

confidence: 94%

“…Tuberculosis (TB) has always been a major health problem in developing countries like India but HIV pandemic has led to resurgence of this disease in developed countries 1 2. Tubercular abscess is a rare presentation of central nervous system (CNS) TB, which commonly presents as tuberculoma or meningitis 1.…”

Section: Introductionmentioning

confidence: 99%

“…Tubercular abscess is a rare presentation of central nervous system (CNS) TB, which commonly presents as tuberculoma or meningitis 1. Treatment of tubercular abscess includes antitubercular chemotherapy and surgical excision 2. Most of the published cases of tubercular brain abscess have been dealt with by surgical treatment along with medical management 1 2.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Clinicoradiological improvement of intracranial tubercular abscess with medical management alone

et al. 2014

View full text Add to dashboard Cite

Tubercular abscess is a rare presentation of central nervous system tuberculosis (TB), which commonly presents as tuberculoma or meningitis. Most of the published cases of tubercular brain abscess have been dealt with by surgical treatment along with medical management. We here report a case of intracranial tubercular abscess in a 17-year-old girl presenting with fever, headache and right hemiparesis who showed significant clinicoradiological improvement with medical management alone. Thus, in a country like India where TB is highly endemic, TB should be considered as a possible aetiology for any intracranial lesion with radiological appearance suggestive of an abscess and surgical treatment can be kept as an option in case of neurological deficits, hydrocephalus or treatment failure.

show abstract