crotal infection with Mycobacterium tuberculosis is unusual, occurring in about 7% of patients with tuberculosis, 1 although its incidence is increasing worldwide in association with human immunodeficiency virus infection. We report a rare case of tuberculous orchiepididymitis in a patient who received intravesical instillation therapy with BCG vaccine after bladder tumor resection and describe the benefits of Doppler sonography for the study of orchiepididymitis.Received March 16, 2007, from the Radiology Service (E.M.B.-G., A.G.-P., G.A.-B., I.A.-M., M.M.M.) and Emergency (R.S.-V.) and Pathology (V.M.-R.) Departments, Carlos Haya Hospital, Malaga, Spain. Manuscript accepted for publication March 26, 2007. Address correspondence to Eva M. Briceño-García, MD, C/ Lingüista Manuel Seco 3, 29016 Malaga, Spain. E-mail: evambriceno@hotmail.com
Case ReportThe patient was a 75-year-old man who underwent transurethral resection of a bladder tumor (grade 3, noninvasive papillary urothelial carcinoma) and benign prostatic nodular hyperplasia. One month later, he started adjuvant therapy with intravesical instillations of BCG: an induction phase of 1 instillation weekly for 4 weeks with 25 mg of InmuCyst (Aventis Pasteur, Lyon, France) followed by monthly booster instillations. Two weeks after the first booster dose, he had pain and tumefaction of the right scrotum. Conventional treatment was given with nonsteroidal anti-inflammatory drugs and antibiotics, ciprofloxacin for 2 weeks and amoxicillin-clavulanic acid for another 2 weeks, resulting in slight improvement of the symptoms and the inflammation, although the testicle and epididymis remained enlarged. The patient underwent a sonographic study with a Philips SD800 7.5-MHz transducer (Philips Medical Systems, Bothell, WA), which showed an enlarged right epididymis, especially the tail, with heterogeneous hypoechogenicity (Figure 1). A hypoechoic nodule was detected on its head. The lower portion of the testicle was also hypoechoic, with the epididymal tail poorly outlined. Color Doppler imaging showed no notable increase in the vascularization of the nodules.