1979
DOI: 10.1001/jama.241.3.264
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Tuberculous meningitis

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Cited by 63 publications
(23 citation statements)
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“…These changes jeopardize arterial blood flow causing ischemia and CI [18,19,20]. Complicating hydrocephalus may stretch blood vessels, further aggravating cerebral ischemia [4, 21, 22]. Nevertheless, there is no evidence that decompressive procedures for hydrocephalus can prevent CI in TBM [23].…”
Section: Discussionmentioning
confidence: 99%
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“…These changes jeopardize arterial blood flow causing ischemia and CI [18,19,20]. Complicating hydrocephalus may stretch blood vessels, further aggravating cerebral ischemia [4, 21, 22]. Nevertheless, there is no evidence that decompressive procedures for hydrocephalus can prevent CI in TBM [23].…”
Section: Discussionmentioning
confidence: 99%
“…Tuberculous meningitis (TBM) is potentially fatal with risks of severe neurological sequelae despite availability of effective antituberculous (anti-TB) drugs [1,2,3,4,5,6,7,8,9,10]. Neurological complications of TBM are diverse and include raised intracranial pressure, cranial neuropathies, optic neuropathy, hydrocephalus, epilepsy, hypopituitarism, spinal arachinoiditis, myelopathy and radiculopathy [1,2,3,4,5,6,7,8,9,10,11,12,13].…”
Section: Introductionmentioning
confidence: 99%
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“…The validity of these criteria has been tested using information from bacterial isolation, polymerase chain reaction test for tuberculosis, response to treatment and autopsy findings. The patients were classified as definite, highly probable and probable tubercular meningitis based upon these criteria and were further staged clinically into stage 1, 2 or 3 as described by Kennedy et al [10]. Clinical staging was based on level of consciousness and focal neurological signs.…”
Section: Methodsmentioning
confidence: 99%
“…Using solid media, the time to detection of colonies may be 4 to 6 weeks. Culturing large volumes of CSF (10-30 mL) on three separate occasions in special liquid media increases the yield of a positive culture from about 30% to over 75% [25]. High-speed centrifugation (3000 x gravity of centrifugal force for 30 minutes) of CSF to pellet the mycobacteria should also increase the rate of culture positivity.…”
Section: Diagnosis Of Tbmmentioning
confidence: 99%