Tuberculous myocarditis presenting as sudden cardiac death

Chan, Alexander C.L.; Dickens, Paul

doi:10.1016/0379-0738(92)90044-w

Cited by 29 publications

(23 citation statements)

References 2 publications

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“…In our case, the lesions were distributed in the lungs, liver, kidneys, spleen, and mesenteric lymph nodes. 5 Tuberculosis-related sudden death (TBRSD) is a rare outcome of TB. The possible causes include TB bronchopneumonia, massive hemoptysis, TB myocarditis, and adrenal insufficiency secondary to TB adrenalitis.…”

Section: Discussionmentioning

confidence: 99%

Miliary Tuberculosis as a Cause of Sudden Death in a Patient Misdiagnosed With Depression

Salem¹,

Mesrati²,

Hadhri³

et al. 2016

Infect Dis Clin Pract

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Introduction Today, miliary spread remains one of the world's most lethal infectious diseases. Despite the availability of effective treatment for most cases, it is still a cause of death in our environment. Some cases of active tuberculosis (TB) are not identified until the patient is dead and an autopsy has been performed. We report an autopsy case of miliary TB and discuss the mechanism of death. Case Report N.M. is a 24-year-old woman without any relevant personal medical or family history. She was admitted with fever of 40 days' duration. The fever was irregular, higher at nights, and associated with headache and anorexia. The patient did not give any history of coughing, hemoptysis, sore throat, joint pains, skin rash, abdominal pain, or rheumatic heart disease. The examination and the radiological investigations did not show any abnormalities. The patient was symptomatically medicated and allowed to return home. After 1 week, she was discovered dead in her bed. A forensic autopsy was requested. At necropsy, the lungs, liver, spleen, and kidneys were macroscopically palish, heterogeneous, and dotted with myriad of small seeds (1–2 mm). Mesentery was the seat of a large firm mass, adhering to the intestinal walls and the pancreas. The diagnosis of miliary TB was confirmed by histological examination. The toxicological screening was negative. Conclusions Our case highlights a rare but important complication of TB, which is “TB-related sudden death.” There is a need for more awareness of the disease, especially in the light of recent reports showing a growing incidence of extrapulmonary TB.

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Section: Discussionmentioning

confidence: 99%

Miliary Tuberculosis as a Cause of Sudden Death in a Patient Misdiagnosed With Depression

Salem¹,

Mesrati²,

Hadhri³

et al. 2016

Infect Dis Clin Pract

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show abstract

“…11 Dickens and Chan reported a case of sudden death in a 71 yr old Chinese male, which on autopsy was diagnosed as miliary tuberculosis with tubercular myocarditis. 12 Bronchiectesis is yet another complication of tuberculosis resulting in sudden death. It presents as chronic cough with purulent expectoration.…”

Section: Discussionmentioning

confidence: 99%

Sudden death due to tuberculosis

Menon

Rastogi

Khadilkar

2007

Journal of Forensic and Legal Medicine

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“…According to Rose AG, the first report of myocardial tuberculosis was made by Maurocordat in 1664 [6]. Since then, other cases have been reported but they are nevertheless very unusual [3][4][5][6]. According to the revised literature, to date this is the first report of tuberculous coronary arteritis leading to sudden death.…”

mentioning

confidence: 88%

“…The incidence of tuberculosis myocarditis oscillates from 0.14% to 0.44%, and tuberculous coronarian arteritis is considered an extremely unusual event. It is known that M. tuberculosis shows low affinity for myocardium [3,4].…”

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confidence: 99%