Tuberculous osteomyelitis of the sternum in an infant: A case report and review of the literature

Kutty, S.; Bennett, Derek; Devitt, Aiden; Dowling, F

doi:10.1046/j.1328-8067.2001.01519.x

Cited by 10 publications

(11 citation statements)

References 9 publications

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“…As a result, 76 articles[ 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 ] were obtained, including 56 (73.7%) case reports,[ 1 3 4 5…”

Section: Resultsmentioning

confidence: 99%

“…A total of 107 (67.3%) cases were primary,[ 2 5 9 10 13 14 16 17 18 19 21 22 23 28 30 31 32 33 34 38 39 40 42 43 44 48 50 52 53 56 59 60 61 62 64 65 66 67 69 70 72 73 74 75 76 ] 33 (20.8%) were secondary,[ 6 11 12 15 20 24 25 26 29 35 37 46 47 51 55 62 64 66 67 ] and 19 (11.9%) were postoperative. [ 1 3 4 7 8 27 36 41 45 49 54 58 62 63 68 …”

Section: Resultsmentioning

confidence: 99%

“…The underlying causes for secondary sternal TB were a previous history of lung TB in 12 (36.4%)[ 15 25 55 62 66 67 73 ] (one was reactivated lung TB[ 73 ] and one was associated with lymph node TB[ 55 ]), TB contact in 10 (30.3%),[ 20 24 46 47 66 ] extrapulmonary TB in six (18.2%) including TB lymphadenitis in three[ 6 51 55 ] (cervical,[ 55 ] supraclavicular,[ 6 ] and unstated[ 51 ] in one each) and vertebral TB,[ 67 ] multifocal skeletal TB,[ 67 ] and abdominal and spinal TB[ 37 ] in one each; and Bacille de Calmette et Guérin vaccination in five (15.2%) patients. [ 11 12 26 29 35 ]…”

Section: Resultsmentioning

confidence: 99%

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Sternal mycobacterial infections

Yuan

2016

Ann Thorac Med

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Sternal mycobacterial infections are rare. Due to the rarity, its clinical characteristics, diagnoses, and regular management strategies are still scanty. A total of 76 articles on this topic were obtained by a comprehensive literature collection. The clinical features, diagnosis, management strategies and prognosis were carefully analyzed. There were totally 159 patients including 152 (95%) cases of tuberculosis (TB) and seven (5%) cases of non-TB sternal infections. Sternal mycobacterial infections can be categorized into three types: Primary, secondary, and postoperative, according to the pathogenesis; and categorized into isolated, peristernal, and multifocal, according to the extent of the lesions. Microbiological investigation is more sensitive than medical imaging and Mantoux tuberculin skin test in the diagnosis of sternal infections. Most patients show good responses to the standard four-drug regimen and a surgical intervention was necessary in 28.3% patients. The prognoses of the patients are good with a very low mortality. A delayed diagnosis of sternal mycobacterial infections may bring about recurrent sternal infections and sustained incurability. An early diagnosis and prompt antibiotic regimens may significantly improve the patients' outcomes.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

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Sternal mycobacterial infections

Yuan

2016

Ann Thorac Med

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“…In endemic areas Mycobacterium tuberculosis infection may occur both as a primary event [11] and disseminated bacille CalmetteGuérin infection postvaccination may involve the sternum [12]. Rarer causative organisms include Aspergillus fumigatus in the immunocompromised patient [13] and Candida albicans seen in debilitated patients poststernotomy [14].…”

Section: Discussionmentioning

confidence: 99%

Primary sternal osteomyelitis: a case series and review of the literature

Upadhyaya¹,

Keil²,

Thonell³

et al. 2005

Journal of Pediatric Surgery

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“…Mycobacterium tuberculosis in endemic areas [12], Aspergillus fumigatus in immunocompromised patients [13] and Candida albicans [14] have also been reported to cause sternal osteomyelitis. In our case report apart of Streptococcus pneumoniae , Enterococcus Species was also isolated, an organism that has never been reported before as an infecting cause of primary sternal osteomyelitis in the international literature.…”

Section: Discussionmentioning

confidence: 99%

Primary sternal osteomyelitis in a 40 days old infant: a case report and review of the literature

Pettas

Apostolopoulos

Flieger

et al. 2009

Cases J

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IntroductionPrimary sternal osteomyelitis is extremely rare in children and only very few cases have been reported in the international literature.Case presentationA 40 days old Caucasian infant was referred to our clinic with a 4 days history of fever and malaise, accompanying a painful swelling of four days duration involving the lower end of the sternum. Examination revealed a 2 cm swelling which was fixed to the underlying bone. A full blood count, erythrocyte sedimentation rate, and C-reactive protein were measured and x-rays (Anterior and Lateral views) and Ultrasound was performed. Blood cultures were also taken. The patient was commenced empirically to Vancomycin and Cefotaxime intravenously.The values of White Blood Cell (16,720), erythrocyte sedimentation rate (132 mm) and C-reactive protein (108 mg/dl) were elevated, the X-rays showed bone destruction and dislocation of the 3rd sternal nuclei and in the U/S performed appeared a soft tissue mass measuring 2,37/1,02 cm related to the periosteum. Surgical debridement was then performed and swab cultures were taken intraoperatively. The infant grew Streptococcus Pneumoniae and Enterococcus Species. The infant was discharged after 25 days from the hospital. He gradually improved over a period of 2 months, became pain free and repeated x-rays showed significant bone resolution.ConclusionPrimary osteomyelitis in infants is a very rare condition that usually resolves with antibiotic therapy and surgical debridement.

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Tuberculous osteomyelitis of the sternum in an infant: A case report and review of the literature

Cited by 10 publications

References 9 publications

Sternal mycobacterial infections

Sternal mycobacterial infections

Primary sternal osteomyelitis: a case series and review of the literature

Primary sternal osteomyelitis in a 40 days old infant: a case report and review of the literature

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