Tuberculous peritonitis

Kushima, Hisako; Sakamoto, Ryohei; Kinoshita, Yoshiaki; Ishii, Hiroshi

doi:10.1136/bcr-2021-245311

Cited by 5 publications

(4 citation statements)

References 3 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…TBP, which is a rare cause of ascites, is seen at a rate of 10%, especially in underdeveloped countries. Ascites related to TBP were detected in our study at a rate of 7,9%, which is important because it shows that TBP is a more important etiological cause in our country than in Western countries [2][3][4].…”

Section: Discussionmentioning

confidence: 47%

“…The diagnosis of TBP is made by clinical, immunological, microbiological, and, most importantly, histopathological methods. While the frequency of TB is gradually decreasing, there has been an increase in the number of individuals infected with TB as a result of the immunosuppressive Human Immunodeficiency Virus (HIV) infection, the increase in malignancies, and the effect of socioeconomic conditions [1][2][3][4].…”

mentioning

confidence: 99%

See 1 more Smart Citation

Tuberculous peritonitis: an analysis of case series of 49 consecutive patients

BÜYÜKKURT,

YILMAZ,

ALBAYRAK

et al. 2024

The European Research Journal

View full text Add to dashboard Cite

Objectives: The incidence of tuberculous peritonitis has been reported between 0.1% and 0.7% among all tuberculosis types. This study, it was aimed to evaluate the cases with tuberculous peritonitis, which has an important place in the differential diagnosis of patients with ascites, clinically, biochemically, microbiologically, and histopathologically. Methods: : Forty-nine patients with a definite clinical, radiological, and histopathological diagnosis of tuberculous peritonitis, which formed the basis of our study, were analyzed retrospectively. Results: The mean age of patients with tuberculous peritonitis was found to be 39.45 ± 19.02 years. Purified-protein derivative (PPD) was positive in 23 (72%) of 32 patients with tuberculous peritonitis whose PPD results were recorded, in 9 (28%) PPD results were evaluated as anergic or negative. QuantiFERON-TB Gold In-Tube (QFT-GIT) test was sent in 10 of the patients, the result was positive in 9 (90%) patients and negative in 1 (10%) patient. There were 32 patients in whom tuberculosis polymerase chain reaction (PCR) was studied from ascitic fluid, 7 (22%) of the patients were PCR positive and 25 (78%) negative. Mycobacterium tuberculosis culture positivity was found in 18 (69%) of 26 patients who were biopsied. In total, 29 (59%) of the patients had M. tuberculosis culture positivity. Conclusions: Tuberculous peritonitis constitutes a public health problem in endemic regions of the world and tuberculous peritonitis should be considered in patients presenting with ascites. Despite all diagnostic difficulties, necessary tests, especially peritoneal biopsy, should be performed for early diagnosis, and it should not be forgotten that early initiation of treatment is very important in terms of morbidity and mortality of the disease.

show abstract

Section: Discussionmentioning

confidence: 47%

mentioning

confidence: 99%

Tuberculous peritonitis: an analysis of case series of 49 consecutive patients

BÜYÜKKURT,

YILMAZ,

ALBAYRAK

et al. 2024

The European Research Journal

View full text Add to dashboard Cite

show abstract

“…Tuberculous peritonitis (TBP) and peritoneal carcinomatosis (PC) are two of the most common causes of non-portal hypertensive ascites in developing countries [ 1 , 2 ], and both diseases require accurate recognition for the appropriate management [ 3 , 4 ]. Our previous studies have illustrated ascitic cholesterol and total protein were excellent measures in distinguishing non‐portal hypertensive ascites from portal hypertension (PH) [ 2 , 5 , 6 ].…”

Section: Introductionmentioning

confidence: 99%

Utility of ascitic tumor markers and adenosine deaminase for differential diagnosis of tuberculous peritonitis and peritoneal carcinomatosis

Wei

Xiao

et al. 2022

BMC Gastroenterol

View full text Add to dashboard Cite

Background Differential diagnosis between tuberculous peritonitis and peritoneal carcinomatosis remains challenging in clinical practice; thus, in-patients diagnosed with tuberculous peritonitis or peritoneal carcinomatosis were retrospectively enrolled, and diagnostic values of ascitic tumor markers and adenosine deaminase were determined. Methods Consecutive patients diagnosed with tuberculous peritonitis or peritoneal carcinomatosis were retrospectively enrolled. The pertinent data of 169 patients enrolled were collected. Results A panel of ascitic tumor makers (CEA, CA15-3, CA19-9) had high specificity (96.83%) and accuracy (94.67%) in the differentiation of peritoneal carcinomatosis from tuberculous peritonitis; and ascitic ADA was a good discriminator between these patients, with an accuracy of 91.72%. Combined use of ascitic tumor makers and ADA (ascitic ADA < 22.5 IU/L or ascitic CEA > 3.65 ng/mL or CA15-3 > 42.70 U/mL or CA19-9 > 25.10 U/mL) performed high sensitivity (99.06%) and accuracy (94.08%) for the diagnosis of peritoneal carcinomatosis. In addition, combined ascitic ADA and tumor marker (positive ascitic tumor makers and ADA < 22.50 IU/L) had 100% of the specificity in diagnosing peritoneal carcinomatosis. Conclusions Combined use of ascitic tumor markers and adenosine deaminase showed excellent efficiency in the differential diagnosis between tuberculous peritonitis and peritoneal carcinomatosis, thus these two simple and cost‐effective parameters should be determined when tuberculous peritonitis or peritoneal carcinomatosis was suspected in clinic practice.

show abstract

“…The occurrence of TP can cause multiple infections of surrounding organs and tissues, resulting in organ failure and endangering life safety [ 3 ]. In clinical practice, conservative treatment schemes can usually achieve ideal results for early TP; but most patients have no special clinical symptoms in the early stage and may only show intermittent abdominal pain, diarrhea, etc., and they often miss the best treatment period due to lack of medical and health knowledge [ 4 , 5 ]. For those with severe illness and complicated infection, surgical treatment is needed [ 6 ].…”

Section: Introductionmentioning

confidence: 99%

Expression of Adenosine Deaminase and NLRP3 Inflammasome in Tuberculous Peritonitis and Their Relationship with Clinical Efficacy

Yan

et al. 2022

Disease Markers

View full text Add to dashboard Cite

Objective Tuberculous peritonitis (TP) can cause multiple infections of surrounding organs and tissues, leading to organ failure and endangering life safety. In this research, the relationship between adenosine deaminase (ADA), NLRP3 inflammasome, and TP and its clinical significance will be deeply explored, so as to provide new directions and reliable reference opinions for future clinical diagnosis and treatment. Methods Altogether, 59 TP patients (research group, RG) and 52 non-TP patients (control group, CG) who were admitted to our hospital from May 2014 to June 2018 were regarded as research objects. Ascites samples of RG before treatment (admission) and one month after treatment and CG before treatment were obtained, and the ADA and NLRP3 levels were tested to evaluate the clinical and prognostic significance of the two in TP. Results Before treatment, ADA and NLRP3 in RG were higher than CG ( P < 0.05), and the sensitivity and specificity of combined detection of the two in predicting TP occurrence were 89.83% and 73.08% ( P < 0.05). In addition, ADA and NLRP3 in RG patients were positively correlated with the disappearance time of abdominal pain and ascites ( P < 0.05) and had excellent predictive effect on the adverse reactions during treatment ( P < 0.05). After treatment, both in RG patients decreased, which was inversely proportional to the clinical efficacy ( P < 0.05). Prognostic follow-up manifested that ADA and NLRP3 in relapse patients were higher than those without recurrence after treatment ( P < 0.05). Conclusion The increase of ADA and NLRP3 in TP is relevant to the adverse reactions during treatment, clinical efficacy, and prognosis recurrence after treatment. It can be used as a disease marker to confirm, intervene, and evaluate TP progression promptly.

show abstract

Tuberculous peritonitis

Cited by 5 publications

References 3 publications

Tuberculous peritonitis: an analysis of case series of 49 consecutive patients

Tuberculous peritonitis: an analysis of case series of 49 consecutive patients

Utility of ascitic tumor markers and adenosine deaminase for differential diagnosis of tuberculous peritonitis and peritoneal carcinomatosis

Expression of Adenosine Deaminase and NLRP3 Inflammasome in Tuberculous Peritonitis and Their Relationship with Clinical Efficacy

Contact Info

Product

Resources

About