Tuberous sclerosis complex: a case report

Abstract

Tuberous Sclerosis Complex (TSC) was first described in the late 1800s as a relative of neurofibromatosis, but it has since been identified as a discrete disorder. Patients with TSC typically present with facial adenomas, seizure disorder, and a developmental disability. The syndrome is caused by mutations in either chromosomes 9 or 16, both of which code for cell development and maturation. This case report describes the unique findings of TSC, and suggests areas for future study. By understanding the dental and medical implications of TSC, early intervention may vastly improve a patient's overall quality of life.

Tuberous sclerosis: a case report

“…The development of this disease produces benign tumors that may affect areas of the head, heart, brain, and kidneys 4 . It can be characterized by a triad of developmental disability (in approximately 30% of cases 9 ), epilepsy, and skin tumors 1,5,7‐10 . Neurological lesions are a result of tubers that occur in the brain.…”

“…4 It can be characterized by a triad of developmental disability (in approximately 30% of cases 9 ), epilepsy, and skin tumors. 1,5,[7][8][9][10] Neurological lesions are a result of tubers that occur in the brain. These tuberous growths become sclerotic and calcify over time.…”