Tuberous sclerosis epilepsy and psychosis by adults

First psychotic episode, related to COVID-19 pandemic, in a patient with tuberous sclerosis complex

“…As a matter of fact, a recent study made by María José Valdés-Florida and al, including all the hospitalized patients with reactive psychoses during the first two weeks of quarantine, show that relapses were directly triggered by stress derived from the COVID-19 pandemic [2]. Also, Zulkifli et al identified a case report from Malaysia, of an acute episode of psychosis seemingly precipitated by fear and distress associated with the COVID-19 pandemic, in 31-year-old male patient without previous history of mental disorder, nor substance use [12]. About medical care, there is not a specific treatment for psychosis seen in TSC [17].…”

First psychotic episode, related to COVID‐19 pandemic, in a patient with tuberous sclerosis complex

“…As a matter of fact, a recent study made by María José Valdés‐Florida and al, including all the hospitalized patients with reactive psychoses during the first two weeks of quarantine, shows that relapses were directly triggered by stress derived from the COVID‐19 pandemic 2 . Also, Zulkifli et al identified a case report from Malaysia, of an acute episode of psychosis seemingly precipitated by fear and distress associated with the COVID‐19 pandemic, in 31‐year‐old male patient without previous history of mental disorder, nor substance use 12 . About medical care, there is not a specific treatment for psychosis seen in TSC 17 .…”

“…According to Andrej N Ilanković et al, 5 patients with the average age of 35, 7 years, from different part of Yugoslavia, who were admitted between 2013 and 2016, developed paranoid psychotic episodes one year before being hospitalized. 12 In fact, hallucinations and delusions are explained based on tubers impinging upon various limbic structures. Subependymal calcification, giant cell tumors, and retinal phakomas might be also the cause.…”

“… 2 Also, Zulkifli et al identified a case report from Malaysia, of an acute episode of psychosis seemingly precipitated by fear and distress associated with the COVID‐19 pandemic, in 31‐year‐old male patient without previous history of mental disorder, nor substance use. 12 About medical care, there is not a specific treatment for psychosis seen in TSC. 17 In literature, a case was reported responding well to risperidone without side effects.…”