2019
DOI: 10.1016/j.sjopt.2019.07.005
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Tubular apocrine adenoma of the eyelid – A case report and literature review

Abstract: Tubular apocrine adenoma is a rare benign adnexal neoplasm most commonly identified in the scalp, composed of a dermal proliferation of apocrine tubules in a background of hyalinized stroma. Tubular apocrine adenoma can be a component of various sweat gland tumors and can also morphologically overlap with other sweat gland neoplasms. Isolated tubular apocrine adenoma arising in the glands of Moll is exceedingly rare, with only 4 previously reported cases. We present a 63-year-old male with tubular apocrine ade… Show more

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Cited by 3 publications
(2 citation statements)
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“…Eyelid lesions that exhibit decapitation secretion have been described in such diverse entities as apocrine tubular adenoma, 3 hidradenoma, 4 pleomorphic adenoma, 5 and adenocarcinoma. 4,6 When decapitation is absent due to chronic hydrostatic pressure within a cyst lumen, the apocrine derivation may be inferred from the presence of the bilayer and supported by the positivity of characteristic immunostains such as GDCFP-15 (Gross Cystic Disease Fluid Protein 15) and CK7.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…Eyelid lesions that exhibit decapitation secretion have been described in such diverse entities as apocrine tubular adenoma, 3 hidradenoma, 4 pleomorphic adenoma, 5 and adenocarcinoma. 4,6 When decapitation is absent due to chronic hydrostatic pressure within a cyst lumen, the apocrine derivation may be inferred from the presence of the bilayer and supported by the positivity of characteristic immunostains such as GDCFP-15 (Gross Cystic Disease Fluid Protein 15) and CK7.…”
Section: Discussionmentioning
confidence: 99%
“…11 Mammaglobin, a marker used to distinguish cutaneous and mammary apocrine carcinoma, usually—but not always—positive in the former and negative in the latter, 11 has not been studied in benign eyelid apocrine tumors except for a single case of tubular adenoma. 3 GATA3, once considered a specific immunohistochemical marker for mammary and urothelial carcinoma, has been demonstrated in normal skin and a wide range of benign and malignant epithelial tumors. 12 The Ki67 proliferation marker is useful in confirming the benign tumor pattern after reviewing its cellularity with hematoxylin-eosin staining.…”
Section: Discussionmentioning
confidence: 99%