Tubular carcinoma of the breast: mode of presentation, mammographic appearance, and frequency of nodal metastases.

Elson, B C; Helvie, Mark A.; Frank, Tracy D.; Wilson, Todd E.; Adler, Dorit D.

doi:10.2214/ajr.161.6.8249721

Cited by 64 publications

(42 citation statements)

References 9 publications

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“…The mammography and sonography characteristics of this rare tumor have been discussed in several reports (5,9,10,11,23). The described features on MG and US were not specific for TC with suspicion of malignancy.…”

Section: Discussionmentioning

confidence: 98%

“…Despite these tumors may be discovered as large palpable masses, they are usually detected when they are less than 1 cm in diameter (8). Ultrasonography (US) or mammography (MG) features of TC have been described a few times (9)(10)(11)(12), however, little has been published about its magnetic resonance (MR) imaging appearance (13,14). The most frequent mammographic finding of tubular carcinoma has been described as an irregular shaped mass with spiculated margins.…”

Section: Introductionmentioning

confidence: 99%

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MR Imaging Features of Tubular Carcinoma: Preliminary Experience in Twelve Masses

Yılmaz

Bayramoğlu

Emirikçi

et al. 2018

Eur J Breast Health

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Objective: We retrospectively analyzed the magnetic resonance (MR) imaging features and diffusion-weighted imaging findings of the 12 masses of 10 patients with tubular carcinoma (TC), including mammography and sonography findings. Materials and Methods:Mammographic, sonographic and magnetic resonance imaging features in 12 histopathologically confirmed masses diagnosed as TC of the breast within 10 patients were evaluated. Morphologic characteristics, enhancement features, apparent diffusion coefficient (ADC) values were reviewed.Results: On mammography (n=5), TC appeared as high density masses with indistinct, spiculated or obscured margins. Sonographically, TC appeared as a hypoechoic appearance (n=12) with posterior acoustic shadowing in nine. On MR imaging, the margins of ten of twelve masses were irregular. Internal enhancement patterns were heterogeneous in 10 patients. Dynamic enhancement patterns illustrated plateau kinetics (n=8). On the T2-weighted images 4 masses were hypointense, and 8 were hyperintense; hypointense internal septation was found in seven of these. Tubular carcinoma appeared as hyperintense on diffusion-weighted imaging with ADC values of 0.85±0.16x10-3 mm 2 /s that was lower than the normal parenchyma of 1.25±0.25x10-3 mm 2 /s. Conclusion:According to our study with a limited number of cases, tubular carcinomas can be described as hyperintense breast carcinomas with or without dark internal septation like appearance on T2-weighted images. Low ADC values from DW imaging can be used to differentiate TC from hyperintense benign breast lesions.

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Section: Discussionmentioning

confidence: 98%

Section: Introductionmentioning

confidence: 99%

MR Imaging Features of Tubular Carcinoma: Preliminary Experience in Twelve Masses

Yılmaz

Bayramoğlu

Emirikçi

et al. 2018

Eur J Breast Health

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“…The only two studies which specifically addressed the risk of axillary involvement in tubular carcinoma of the breast have reported conflicting results. Although McDivitt et al [23] found that a mean tumor size of 1.5 cm was significant for axillary involvement, Elson et al [24] reported that metastatic axillary carcinoma was found in four of 14 (29%) patients with tubular cancer and a median size of 8 mm.…”

Section: Discussionmentioning

confidence: 99%

Clinical observations of axillary involvement for tubular, lobular, and ductal carcinomas of the breast

Leonard¹,

Philpott²,

Shapiro³

et al. 1999

J. Surg. Oncol.

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“…[33][34][35][36] Mammographic calcifications often are the reason for biopsy and represent calcifications present within the tubular carcinoma. Tubular carcinoma can also be an incidental finding in a biopsy performed for calcifications that are present in an adjacent benign proliferation, such as columnar cell change.…”

Section: Tubular Carcinomamentioning

confidence: 99%

“…Tubular carcinoma can also be an incidental finding in a biopsy performed for calcifications that are present in an adjacent benign proliferation, such as columnar cell change. [34][35][36] Similar to other invasive carcinomas, ultrasound shows an ill-defined hypoechoic mass with shadowing. 36 On 20 Tumors with a proportion of tubules that is significant but constitutes less than 90% of the tumor may be designated as a ''mixed'' tubular carcinoma or a well-differentiated carcinoma with tubular features.…”

Section: Tubular Carcinomamentioning

confidence: 99%

Small Glandular Proliferations of the Breast With Absent or Attenuated Myoepithelial Reactivity by Immunohistochemistry: A Review Focusing on the Differential Diagnosis and Interpretative Pitfalls

Ginter

Shin²,

D’Alfonso³

2016

Archives of Pathology &Amp; Laboratory Medicine

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Context.—Small glandular proliferations of the breast encompass a variety of benign, atypical, and malignant lesions that show some overlapping morphologic features. Myoepithelial stains are frequently used in the workup of these lesions in order to rule out or establish a diagnosis of invasive carcinoma. Some benign lesions show absent or diminished myoepithelial staining, and may represent an interpretative pitfall, particularly in small core biopsy samples. Objective.—To review small glandular proliferations of the breast that show absent or diminished staining with myoepithelial immunohistochemical markers. Data Sources.—The study comprised a review of published literature and clinical case material. Conclusions.—The interpretation of myoepithelial stains in small glandular proliferations of the breast can, on some occasions, represent a challenge in diagnosing these lesions. Recognition of the key histopathologic features and immunohistochemical staining patterns of the entities in the differential diagnosis is crucial in their workup.

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Tubular carcinoma of the breast: mode of presentation, mammographic appearance, and frequency of nodal metastases.

Cited by 64 publications

References 9 publications

MR Imaging Features of Tubular Carcinoma: Preliminary Experience in Twelve Masses

MR Imaging Features of Tubular Carcinoma: Preliminary Experience in Twelve Masses

Clinical observations of axillary involvement for tubular, lobular, and ductal carcinomas of the breast

Small Glandular Proliferations of the Breast With Absent or Attenuated Myoepithelial Reactivity by Immunohistochemistry: A Review Focusing on the Differential Diagnosis and Interpretative Pitfalls

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